| Product Number |
ARP34747_P050-FITC |
| Product Page |
www.avivasysbio.com/egln2-antibody-n-terminal-region-fitc-arp34747-p050-fitc.html |
| Name |
EGLN2 Antibody - N-terminal region : FITC (ARP34747_P050-FITC) |
| Protein Size (# AA) |
146 amino acids |
| Molecular Weight |
16kDa |
| Conjugation |
FITC: Fluorescein Isothiocyanate |
| NCBI Gene Id |
112398 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Egl nine homolog 2 (C. elegans) |
| Alias Symbols |
EIT6, PHD1, EIT-6, HPH-1, HPH-3, HIFPH1, HIF-PH1 |
| Peptide Sequence |
Synthetic peptide located within the following region: MCLPSPSKPTSLHPCQAMVACYPGNGLGYVRHVDNPHGDGRCITCIYYLN |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
| Description of Target |
The hypoxia inducible factor (HIF) is a transcriptional complex which is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. EGLN2 encodes an enzyme responsible for this posttranslational modification. Alternative splicing of EGLN2 results in three transcript variants encoding different isoforms. |
| Protein Interactions |
SRPK2; CEP192; IKBKG; FAM46A; EPAS1; A2M; MAGEA11; SIAH2; LPP; WTIP; AJUBA; LIMD1; TRIP6; SPRY2; PRPF19; EGLN3; EGLN2; HIF1A; HIF3A; MOB4; POLR2A; |
| Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Datasheets/Manuals |
Printable datasheet for anti-EGLN2 (ARP34747_P050-FITC) antibody |
| Blocking Peptide |
For anti-EGLN2 (ARP34747_P050-FITC) antibody is Catalog # AAP34747 (Previous Catalog # AAPP05941) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human EGLN2 |
| Uniprot ID |
Q96KS0 |
| Protein Name |
Egl nine homolog 2 |
| Publications |
Gilbert, J. S., Banek, C. T., Bauer, A. J., Gingery, A. & Needham, K. Exercise training attenuates placental ischemia-induced hypertension and angiogenic imbalance in the rat. Hypertension 60, 1545-51 (2012). WB, Bovine, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse, Rat, Human, Zebrafish, Sheep 23090773 |
| Protein Accession # |
EAW57007 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_053046 |
| Gene Symbol |
EGLN2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 86%; Zebrafish: 93% |
| Image 1 | |
