EGLN2 Antibody - N-terminal region (ARP34747_P050)

Data Sheet
 
Product Number ARP34747_P050
Product Page www.avivasysbio.com/egln2-antibody-n-terminal-region-arp34747-p050.html
Name EGLN2 Antibody - N-terminal region (ARP34747_P050)
Protein Size (# AA) 146 amino acids
Molecular Weight 16kDa
NCBI Gene Id 112398
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Egl nine homolog 2 (C. elegans)
Alias Symbols EIT6, PHD1, EIT-6, HPH-1, HPH-3, HIFPH1, HIF-PH1
Peptide Sequence Synthetic peptide located within the following region: MCLPSPSKPTSLHPCQAMVACYPGNGLGYVRHVDNPHGDGRCITCIYYLN
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Description of Target The hypoxia inducible factor (HIF) is a transcriptional complex which is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. EGLN2 encodes an enzyme responsible for this posttranslational modification. Alternative splicing of EGLN2 results in three transcript variants encoding different isoforms.
Protein Interactions SRPK2; CEP192; IKBKG; FAM46A; EPAS1; A2M; MAGEA11; SIAH2; LPP; WTIP; AJUBA; LIMD1; TRIP6; SPRY2; PRPF19; EGLN3; EGLN2; HIF1A; HIF3A; MOB4; POLR2A;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-EGLN2 (ARP34747_P050) antibody
Blocking Peptide For anti-EGLN2 (ARP34747_P050) antibody is Catalog # AAP34747 (Previous Catalog # AAPP05941)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human EGLN2
Uniprot ID Q96KS0
Protein Name Egl nine homolog 2
Publications

Gilbert, J. S., Banek, C. T., Bauer, A. J., Gingery, A. & Needham, K. Exercise training attenuates placental ischemia-induced hypertension and angiogenic imbalance in the rat. Hypertension 60, 1545-51 (2012). 23090773

Protein Accession # EAW57007
Purification Affinity Purified
Nucleotide Accession # NM_053046
Tested Species Reactivity Human
Gene Symbol EGLN2
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 86%; Zebrafish: 93%
Image 1
Human Heart
WB Suggested Anti-EGLN2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human heart
 

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