| Product Number |
ARP34661_P050-FITC |
| Product Page |
www.avivasysbio.com/amot-antibody-n-terminal-region-fitc-arp34661-p050-fitc.html |
| Name |
AMOT Antibody - N-terminal region : FITC (ARP34661_P050-FITC) |
| Protein Size (# AA) |
675 amino acids |
| Molecular Weight |
72kDa |
| Conjugation |
FITC: Fluorescein Isothiocyanate |
| NCBI Gene Id |
154796 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Angiomotin |
| Alias Symbols |
KIAA1071 |
| Peptide Sequence |
Synthetic peptide located within the following region: TANKQLAEKEYEGSEDTRKTISQLFAKNKESQREKEKLEAELATARSTNE |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
| Reference |
Holmgren,L., (2006) Proc. Natl. Acad. Sci. U.S.A. 103 (24), 9208-9213 |
| Description of Target |
AMOT belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Protein Interactions |
AMOT; C1orf216; WDYHV1; MED4; SNAPC5; PPP2R4; LURAP1; UNC119; LMO4; PIN1; MAGEA4; KRT31; KRT15; FUS; SEPT1; CEP76; HAUS2; LATS2; CEP250; CDKN1A; ACTB; ACTA1; YAP1; SART3; AURKB; MAPK3; BAG3; WWOX; ITCH; LATS1; YWHAG; UBC; PARK2; AMOTL1; SPICE1; MPP7; CNTR |
| Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Datasheets/Manuals |
Printable datasheet for anti-AMOT (ARP34661_P050-FITC) antibody |
| Blocking Peptide |
For anti-AMOT (ARP34661_P050-FITC) antibody is Catalog # AAP34661 (Previous Catalog # AAPP23628) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human AMOT |
| Uniprot ID |
Q4VCS5 |
| Protein Name |
Angiomotin |
| Sample Type Confirmation |
AMOT is supported by BioGPS gene expression data to be expressed in HEK293T |
| Protein Accession # |
NP_573572 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_133265 |
| Gene Symbol |
AMOT |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 100% |
| Image 1 | |
|
