KMT5B Antibody - middle region : FITC (ARP34567_P050-FITC)

Data Sheet
 
Product Number ARP34567_P050-FITC
Product Page www.avivasysbio.com/kmt5b-antibody-middle-region-fitc-arp34567-p050-fitc.html
Name KMT5B Antibody - middle region : FITC (ARP34567_P050-FITC)
Protein Size (# AA) 885 amino acids
Molecular Weight 99kDa
Conjugation FITC: Fluorescein Isothiocyanate
NCBI Gene Id 51111
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name lysine methyltransferase 5B
Alias Symbols CGI85, MRD51, CGI-85, SUV420H1
Peptide Sequence Synthetic peptide located within the following region: NNGFNSGSGSSSTKLKIQLKRDEENRGSYTEGLHENGVCCSDPLSLLESR
Product Format Liquid. Purified antibody supplied in 1x PBS buffer.
Reference Twells,R.C., et al., (2001) Genomics 72 (3), 231-241
Description of Target This gene encodes a protein that contains a SET domain. SET domains appear to be protein-protein interaction domains that mediate interactions with a family of proteins that display similarity with dual-specificity phosphatases (dsPTPases). The function of this gene has not been determined. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Protein Interactions SMARCD1; HIST1H4A; YWHAQ;
Reconstitution and Storage All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Datasheets/Manuals Printable datasheet for anti-KMT5B (ARP34567_P050-FITC) antibody
Blocking Peptide For anti-KMT5B (ARP34567_P050-FITC) antibody is Catalog # AAP34567 (Previous Catalog # AAPP05749)
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human SUV420H1
Uniprot ID Q4FZB7
Protein Name histone-lysine N-methyltransferase KMT5B
Publications

Gatta, R. & Mantovani, R. NF-Y substitutes H2A-H2B on active cell-cycle promoters: recruitment of CoREST-KDM1 and fine-tuning of H3 methylations. Nucleic Acids Res. 36, 6592-607 (2008). WB, IHC, IP, ChIP, Human, Rat, Horse, Guinea pig, Mouse, Dog 18940868

Murata, T. et al. Epigenetic histone modification of Epstein-Barr virus BZLF1 promoter during latency and reactivation in Raji cells. J. Virol. 86, 4752-61 (2012). WB, IHC, IP, ChIP, Human, Rat, Horse, Guinea pig, Mouse, Dog 22357272

Purification Affinity Purified
Gene Symbol KMT5B
Predicted Species Reactivity Human, Mouse, Rat, Dog, Guinea Pig, Horse
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Dog: 86%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 91%; Rat: 93%
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