Product Number |
ARP34293_P050 |
Product Page |
www.avivasysbio.com/dpf3-antibody-middle-region-arp34293-p050.html |
Name |
DPF3 Antibody - middle region (ARP34293_P050) |
Protein Size (# AA) |
357 amino acids |
Molecular Weight |
40kDa |
NCBI Gene Id |
8110 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
D4, zinc and double PHD fingers, family 3 |
Alias Symbols |
CERD4, BAF45C |
Peptide Sequence |
Synthetic peptide located within the following region: KDGFTSESTTLEALLRGEGVEKKVDAREEESIQEIQRVLENDENVEEGNE |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Hoyal,C.R., (er) J Carcinog 4, 13 (2005) |
Description of Target |
DPF3 is a muscle-specific component of the BAF complex, a multiprotein complex involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). DPF3 specifically binds acetylated lysines on histone 3 and 4 (H3K14ac, H3K9ac, H4K5ac, H4K8ac, H4K12ac, H4K16ac). In the complex, it acts as a tissue-specific anchor between histone acetylations and methylations and chromatin remodeling. It thereby probably plays an essential role in heart and skeletal muscle development. |
Protein Interactions |
SMARCA4; SMARCA2; RELA; NFKB1; SMARCD1; SMARCC1; SMARCB1; ESRRA; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-DPF3 (ARP34293_P050) antibody |
Blocking Peptide |
For anti-DPF3 (ARP34293_P050) antibody is Catalog # AAP34293 (Previous Catalog # AAPP05643) |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human DPF3 |
Uniprot ID |
Q92784 |
Protein Name |
Zinc finger protein DPF3 |
Publications |
Theodorou, M. et al. Identification of a STAT5 target gene, Dpf3, provides novel insights in chronic lymphocytic leukemia. PLoS One 8, e76155 (2013). 24155890 |
Sample Type Confirmation |
DPF3 is supported by BioGPS gene expression data to be expressed in NCIH226 |
Protein Accession # |
NP_036206 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_012074 |
Tested Species Reactivity |
Human |
Gene Symbol |
DPF3 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
Image 1 | Human NCI-H226
| Host: Rabbit Target Name: DPF3 Sample Type: NCI-H226 Antibody Dilution: 1.0ug/mlDPF3 is supported by BioGPS gene expression data to be expressed in NCIH226 |
|
Image 2 | Human MCF-7
| WB Suggested Anti-DPF3 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive Control: MCF7 cell lysate |
|
Image 3 | Human HT1080
| Host: Rabbit Target Name: DPF3 Sample Type: HT1080 Antibody Dilution: 1.0ug/ml |
|
Image 4 | Human MCF7
| Host: Rabbit Target Name: DPF3 Sample Type: MCF7 Antibody Dilution: 1.0ug/ml |
|
Image 5 | Human HepG2 Whole Cell
| Host: Rabbit Target Name: DPF3 Sample Tissue: Human HepG2 Whole Cell Antibody Dilution: 1ug/ml |
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