| Product Number |
ARP34171_P050-FITC |
| Product Page |
www.avivasysbio.com/smarcb1-antibody-n-terminal-region-fitc-arp34171-p050-fitc.html |
| Name |
SMARCB1 Antibody - N-terminal region : FITC (ARP34171_P050-FITC) |
| Protein Size (# AA) |
385 amino acids |
| Molecular Weight |
44kDa |
| Conjugation |
FITC: Fluorescein Isothiocyanate |
| NCBI Gene Id |
6598 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 |
| Alias Symbols |
RDT, CSS3, INI1, SNF5, Snr1, BAF47, MRD15, RTPS1, Sfh1p, hSNFS, SNF5L1, SWNTS1, PPP1R144 |
| Peptide Sequence |
Synthetic peptide located within the following region: RGSLYKRYPSLWRRLATVEERKKIVASSHGKKTKPNTKDHGYTTLATSVT |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
| Reference |
Mueller,W., et al., (2004) Neuropathol Appl Neurobiol 30 (3), 304-307 |
| Description of Target |
The protein encoded by SMARCB1 is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. SMARCB1 has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. |
| Protein Interactions |
UBC; SOX2; tat; EPAS1; TRA2A; NCSTN; SAP18; EIF4A3; ARID1A; DPF1; VTN; TOP2B; SON; SMARCE1; SMARCD3; SMARCD2; SMARCD1; SMARCC2; SMARCA4; SMARCA2; SMARCC1; ARID1B; HDAC2; APP; PHF10; UBD; COPS5; CUL3; TFAP4; CAND1; RB1CC1; UBB; CEBPB; UL114; UL44; CHFR; DP |
| Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Datasheets/Manuals |
Printable datasheet for anti-SMARCB1 (ARP34171_P050-FITC) antibody |
| Blocking Peptide |
For anti-SMARCB1 (ARP34171_P050-FITC) antibody is Catalog # AAPP05433 |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human SMARCB1 |
| Uniprot ID |
Q12824 |
| Protein Name |
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 |
| Protein Accession # |
NP_003064 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_003073 |
| Gene Symbol |
SMARCB1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100% |
| Image 1 | |
