| Product Number |
ARP34171_P050 |
| Product Page |
www.avivasysbio.com/smarcb1-antibody-n-terminal-region-arp34171-p050.html |
| Name |
SMARCB1 Antibody - N-terminal region (ARP34171_P050) |
| Protein Size (# AA) |
385 amino acids |
| Molecular Weight |
44kDa |
| NCBI Gene Id |
6598 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 |
| Alias Symbols |
RDT, CSS3, INI1, SNF5, Snr1, BAF47, MRD15, RTPS1, Sfh1p, hSNFS, SNF5L1, SWNTS1, PPP1R144 |
| Peptide Sequence |
Synthetic peptide located within the following region: RGSLYKRYPSLWRRLATVEERKKIVASSHGKKTKPNTKDHGYTTLATSVT |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Mueller,W., et al., (2004) Neuropathol Appl Neurobiol 30 (3), 304-307 |
| Description of Target |
The protein encoded by SMARCB1 is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. SMARCB1 has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. |
| Protein Interactions |
UBC; SOX2; tat; EPAS1; TRA2A; NCSTN; SAP18; EIF4A3; ARID1A; DPF1; VTN; TOP2B; SON; SMARCE1; SMARCD3; SMARCD2; SMARCD1; SMARCC2; SMARCA4; SMARCA2; SMARCC1; ARID1B; HDAC2; APP; PHF10; UBD; COPS5; CUL3; TFAP4; CAND1; RB1CC1; UBB; CEBPB; UL114; UL44; CHFR; DP |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-SMARCB1 (ARP34171_P050) antibody |
| Blocking Peptide |
For anti-SMARCB1 (ARP34171_P050) antibody is Catalog # AAPP05433 |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human SMARCB1 |
| Uniprot ID |
Q12824 |
| Protein Name |
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 |
| Protein Accession # |
NP_003064 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_003073 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
SMARCB1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100% |
| Image 1 | Human Liver
 | Human Liver |
|
| Image 2 | Human Thymus
 | WB Suggested Anti-SMARCB1 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Thymus |
|
| Image 3 | Human Lung
 | Rabbit Anti-SMARCB1 Antibody
Catalog Number: ARP34171
Paraffin Embedded Tissue: Human alveolar cell
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
