Product Number |
ARP33902_P050 |
Product Page |
www.avivasysbio.com/kif2a-antibody-n-terminal-region-arp33902-p050.html |
Name |
KIF2A Antibody - N-terminal region (ARP33902_P050) |
Protein Size (# AA) |
706 amino acids |
Molecular Weight |
80kDa |
NCBI Gene Id |
3796 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Kinesin heavy chain member 2A |
Alias Symbols |
HK2, KIF2, CDCBM3 |
Peptide Sequence |
Synthetic peptide located within the following region: IEPSPETPPPPASSAKVNKIVKNRRTVASIKNDPPSRDNRVVGSARARPS |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Jang,C.Y., (2008) J. Cell Biol. 181 (2), 255-267 |
Description of Target |
KIF2A belongs to the kinesin-like protein family, MCAK/KIF2 subfamily. It contains 1 kinesin-motor domain. KIF2A plus end-directed microtubule-dependent motor required for normal brain development. It may regulate microtubule dynamics during axonal growth. KIF2A is implicated in formation of bipolar mitotic spindles. It has microtubule depolymerization activity. Hela cells lacking KIF2A show asymmetric or monopolar mitotic spindles. Osteosarcoma cells (U2OS) lacking KIF2A or KIF2B show disorganised or monopolar mitotic spindles.Kinesins, such as KIF2, are microtubule-associated motor proteins. For background information on kinesins, see MIM 148760.[supplied by OMIM]. |
Protein Interactions |
FAM13C; MRPL53; LARP1B; KIF2A; UBC; WWOX; STK4; HIST3H3; NOTCH1; HDGF; KLC2; CLSTN1; KLC1; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-KIF2A (ARP33902_P050) antibody |
Blocking Peptide |
For anti-KIF2A (ARP33902_P050) antibody is Catalog # AAP33902 (Previous Catalog # AAPP04973) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human KIF2A |
Uniprot ID |
O00139 |
Protein Name |
Kinesin-like protein KIF2A |
Protein Accession # |
NP_004511 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_004520 |
Tested Species Reactivity |
Human |
Gene Symbol |
KIF2A |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 86%; Dog: 93%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 79%; Rabbit: 93%; Rat: 93% |
Image 1 | Human HepG2
| WB Suggested Anti-KIF2A Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: HepG2 cell lysate |
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