KIF2A Antibody - N-terminal region (ARP33902_P050)

Data Sheet
 
Product Number ARP33902_P050
Product Page www.avivasysbio.com/kif2a-antibody-n-terminal-region-arp33902-p050.html
Name KIF2A Antibody - N-terminal region (ARP33902_P050)
Protein Size (# AA) 706 amino acids
Molecular Weight 80kDa
NCBI Gene Id 3796
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Kinesin heavy chain member 2A
Alias Symbols HK2, KIF2, CDCBM3
Peptide Sequence Synthetic peptide located within the following region: IEPSPETPPPPASSAKVNKIVKNRRTVASIKNDPPSRDNRVVGSARARPS
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Jang,C.Y., (2008) J. Cell Biol. 181 (2), 255-267
Description of Target KIF2A belongs to the kinesin-like protein family, MCAK/KIF2 subfamily. It contains 1 kinesin-motor domain. KIF2A plus end-directed microtubule-dependent motor required for normal brain development. It may regulate microtubule dynamics during axonal growth. KIF2A is implicated in formation of bipolar mitotic spindles. It has microtubule depolymerization activity. Hela cells lacking KIF2A show asymmetric or monopolar mitotic spindles. Osteosarcoma cells (U2OS) lacking KIF2A or KIF2B show disorganised or monopolar mitotic spindles.Kinesins, such as KIF2, are microtubule-associated motor proteins. For background information on kinesins, see MIM 148760.[supplied by OMIM].
Protein Interactions FAM13C; MRPL53; LARP1B; KIF2A; UBC; WWOX; STK4; HIST3H3; NOTCH1; HDGF; KLC2; CLSTN1; KLC1;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-KIF2A (ARP33902_P050) antibody
Blocking Peptide For anti-KIF2A (ARP33902_P050) antibody is Catalog # AAP33902 (Previous Catalog # AAPP04973)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human KIF2A
Uniprot ID O00139
Protein Name Kinesin-like protein KIF2A
Protein Accession # NP_004511
Purification Affinity Purified
Nucleotide Accession # NM_004520
Tested Species Reactivity Human
Gene Symbol KIF2A
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 86%; Dog: 93%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 79%; Rabbit: 93%; Rat: 93%
Image 1
Human HepG2
WB Suggested Anti-KIF2A Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate
 

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