| Product Number |
ARP33820_P050 |
| Product Page |
www.avivasysbio.com/asgr2-antibody-n-terminal-region-arp33820-p050.html |
| Name |
ASGR2 Antibody - N-terminal region (ARP33820_P050) |
| Protein Size (# AA) |
311 amino acids |
| Molecular Weight |
35kDa |
| NCBI Gene Id |
433 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
asialoglycoprotein receptor 2 |
| Alias Symbols |
HL-2, HBXBP, ASGPR2, ASGP-R2, CLEC4H2 |
| Peptide Sequence |
Synthetic peptide located within the following region: LVVICVTGSQSEGHRGAQLQAELRSLKEAFSNFSSSTLTEVQAISTHGGS |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Yik,J.H., et al., (2002) J. Biol. Chem. 277 (43), 40844-40852 |
| Description of Target |
This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Protein Interactions |
HDAC3; UBC; CDK6; CDK4; COPS5; TADA3; CDKN2A; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-ASGR2 (ARP33820_P050) antibody |
| Blocking Peptide |
For anti-ASGR2 (ARP33820_P050) antibody is Catalog # AAP33820 (Previous Catalog # AAPP04886) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human ASGR2 |
| Uniprot ID |
P07307 |
| Protein Name |
Asialoglycoprotein receptor 2 |
| Publications |
Chang, T.-C. et al. Synthesis and evaluation of a photoactive probe with a multivalent carbohydrate for capturing carbohydrate-lectin interactions. Bioconjug. Chem. 24, 1895-906 (2013). 24151840 |
| Protein Accession # |
NP_001172 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_001181 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
ASGR2 |
| Predicted Species Reactivity |
Human, Rat, Pig, Yeast |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Human: 100%; Pig: 77%; Rat: 79%; Yeast: 77% |
| Image 1 | Human Lung
 | Rabbit Anti-ANKRD12 Antibody
Catalog Number: ARP33820
Paraffin Embedded Tissue: Human cilia
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
| Image 2 | Human Intestine
 | Human Intestine |
|
| Image 3 | Human Lung
 | WB Suggested Anti-ASGR2 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Lung |
|
