ASGR1 Antibody - middle region : FITC (ARP33805_P050-FITC)

Data Sheet
 
Product Number ARP33805_P050-FITC
Product Page www.avivasysbio.com/asgr1-antibody-middle-region-fitc-arp33805-p050-fitc.html
Name ASGR1 Antibody - middle region : FITC (ARP33805_P050-FITC)
Protein Size (# AA) 291 amino acids
Molecular Weight 33kDa
Conjugation FITC: Fluorescein Isothiocyanate
NCBI Gene Id 432
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Asialoglycoprotein receptor 1
Alias Symbols HL-1, ASGPR, ASGPR1, CLEC4H1
Peptide Sequence Synthetic peptide located within the following region: RKMKSLESQLEKQQKDLSEDHSSLLLHVKQFVSDLRSLSCQMAALQGNGS
Product Format Liquid. Purified antibody supplied in 1x PBS buffer.
Description of Target ASGR1 is a cell surface receptor binds to galactose-terminated glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface.
Protein Interactions CERS2; HIVEP1; SYVN1; VKORC1; FBXO6; EDEM1; HSPA5; CANX; APP; CLEC4G; NLK; RBBP6; HSP90B1; TG; HSP90AA1; DHFR; ASGR2; ITGA1;
Reconstitution and Storage All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Datasheets/Manuals Printable datasheet for anti-ASGR1 (ARP33805_P050-FITC) antibody
Blocking Peptide For anti-ASGR1 (ARP33805_P050-FITC) antibody is Catalog # AAP33805
Immunogen The immunogen is a synthetic peptide directed towards the middle region of Human ASGR1
Uniprot ID P07306
Protein Name Asialoglycoprotein receptor 1
Publications

Chang, T.-C. et al. Synthesis and evaluation of a photoactive probe with a multivalent carbohydrate for capturing carbohydrate-lectin interactions. Bioconjug. Chem. 24, 1895-906 (2013). WB, Human, Pig, Rat, Guinea pig, Mouse, Horse, Bovine, Yeast 24151840

Sample Type Confirmation

ASGR1 is supported by BioGPS gene expression data to be expressed in HepG2

Protein Accession # NP_001662
Purification Affinity Purified
Nucleotide Accession # NM_001671
Gene Symbol ASGR1
Predicted Species Reactivity Human, Mouse, Rat, Cow, Guinea Pig, Horse, Pig, Yeast
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 85%; Guinea Pig: 92%; Horse: 86%; Human: 100%; Mouse: 91%; Pig: 93%; Rat: 92%; Yeast: 75%
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