TOX antibody - N-terminal region (ARP33702_P050)
Data Sheet
 
Product Number ARP33702_P050
Product Page www.avivasysbio.com/tox-antibody-n-terminal-region-arp33702-p050.html
Product Name TOX antibody - N-terminal region (ARP33702_P050)
Gene Symbol TOX
Protein Size (# AA) 526 amino acids
Molecular Weight 58kDa
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Official Gene Full Name Thymocyte selection-associated high mobility group box
Alias Symbols KIAA0808, TOX1
NCBI Gene Id 9760
Host Rabbit
Clonality Polyclonal
Size 100 ul
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Description This is a rabbit polyclonal antibody against TOX. It was validated on Western Blot using a cell lysate as a positive control. Aviva Systems Biology strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (info@avivasysbio.com).
Peptide Sequence Synthetic peptide located within the following region: CLDPYYCNKFDGENMYMSMTEPSQDYVPASQSYPGPSLESEDFNIPPITP
Target Reference Aliahmad,P., (2004) J. Exp. Med. 199 (8), 1089-1099
Description of Target Some high-mobility group (HMG) box proteins (e.g., LEF1) contain a single HMG box motif and bind DNA in a sequence-specific manner, while other members of this family (e.g., HMG1) have multiple HMG boxes and bind DNA in a sequence-independent but structure-dependent manner. All HMG box proteins are able to induce a sharp bend in DNA. TOX contains a single HMG box motif.Some high-mobility group (HMG) box proteins (e.g., LEF1; MIM 153245) contain a single HMG box motif and bind DNA in a sequence-specific manner, while other members of this family (e.g., HMG1; MIM 163905) have multiple HMG boxes and bind DNA in a sequence-independent but structure-dependent manner. All HMG box proteins are able to induce a sharp bend in DNA. TOX contains a single HMG box motif.[supplied by OMIM].
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Lead Time Domestic: within 1-2 days delivery International: 1-2 days
Blocking Peptide For anti-TOX (ARP33702_P050) antibody is Catalog # AAP33702 (Previous Catalog # AAPS08005)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human TOX
Complete computational species homology data Anti-TOX (ARP33702_P050)
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express TOX.
Swissprot Id O94900
Protein Name Thymocyte selection-associated high mobility group box protein TOX
Sample Type Confirmation

TOX is supported by BioGPS gene expression data to be expressed in Jurkat

Protein Accession # NP_055544
Purification Affinity Purified
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express TOX.
Nucleotide Accession # NM_014729
Replacement Item This antibody may replace item sc-374136 from Santa Cruz Biotechnology.
Conjugation Options

ARP33702_P050-FITC Conjugated

ARP33702_P050-HRP Conjugated

ARP33702_P050-Biotin Conjugated

CB Replacement sc-374136; sc-374137; sc-98180
Species Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 92%
Image 1
Human Jurkat
WB Suggested Anti-TOX Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysateTOX is supported by BioGPS gene expression data to be expressed in Jurkat
 

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