| Product Number |
ARP33623_P050 |
| Product Page |
www.avivasysbio.com/cldn1-antibody-c-terminal-region-arp33623-p050.html |
| Name |
CLDN1 Antibody - C-terminal region (ARP33623_P050) |
| Protein Size (# AA) |
211 amino acids |
| Molecular Weight |
23 kDa |
| NCBI Gene Id |
9076 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Claudin 1 |
| Description |
|
| Alias Symbols |
CLD1, SEMP1, ILVASC |
| Peptide Sequence |
Synthetic peptide located within the following region: GQALFTGWAAASLCLLGGALLCCSCPRKTTSYPTPRPYPKPAPSSGKDYV |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Coyne,C.B., et al., (2003) Am. J. Physiol. Lung Cell Mol. Physiol. 285 (5), L1166-L1178 |
| Description of Target |
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This protein, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. |
| Protein Interactions |
UBC; DRG1; LNX1; TJP3; BRD4; MPDZ; TJP2; CLDN1; INADL; CLDN3; WNK4; TJP1; MMP14; MMP2; CLDN5; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Enhanced Validation |
|
| Datasheets/Manuals |
Printable datasheet for anti-CLDN1 (ARP33623_P050) antibody |
| Blocking Peptide |
For anti-CLDN1 (ARP33623_P050) antibody is Catalog # AAP33623 (Previous Catalog # AAPP04679) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human CLDN1 |
| Uniprot ID |
O95832 |
| Protein Name |
Claudin-1 |
| Protein Accession # |
NP_066924 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_021101 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
CLDN1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%; Sheep: 100% |
| Image 1 | Human Liver
 | Human Liver |
|
| Image 2 | Human MCF7 Whole Cell
 | Host: Rabbit
Target Name: CLDN1
Sample Tissue: Human MCF7 Whole Cell
Antibody Dilution: 3ug/ml |
|
| Image 3 | Human MCF7 Whole Cell
 | Host: Rabbit
Target Name: CLDN1
Sample Tissue: Human MCF7 Whole Cell
Antibody Dilution: 3ug/ml |
|
| Image 4 | Human Hela Whole Cell
 | Host: Rabbit
Target Name: CLDN1
Sample Tissue: Human Hela Whole Cell
Antibody Dilution: 1ug/ml |
|
