TBX3 Antibody - middle region (ARP33411_P050)

• Product Number: ARP33411_P050
• Name: TBX3 Antibody - middle region (ARP33411_P050)
• Protein Size (# AA): 743 amino acids
• Molecular Weight: 79kDa
• NCBI Gene Id: 6926
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: T-box 3
• Alias Symbols: UMS, XHL, TBX3-ISO
• Peptide Sequence: Synthetic peptide located within the following region: VGTSNLKDLCPSEGESDAEAESKEEHGPEACDAAKISTTTSEEPCRDKGS
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Reference: Yarosh,W., (2008) Cancer Res. 68 (3), 693-699
• Description of Target: TBX3 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined.This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined.
• Protein Interactions: CA8; AES; SOX2; Dlg4; ELAVL1; HDAC5; HDAC3; HDAC2; HDAC1; TOLLIP; TBX3;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-TBX3 (ARP33411_P050) antibody is Catalog # AAP33411 (Previous Catalog # AAPP04457)
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TBX3
• Uniprot ID: O15119
• Protein Name: T-box transcription factor TBX3
• Protein Accession #: NP_057653
• Purification: Affinity Purified
• Nucleotide Accession #: NM_016569
• Tested Species Reactivity: Human
• Gene Symbol: TBX3
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
• Application: IHC, WB
• Predicted Homology Based on Immunogen Sequence: Cow: 92%; Dog: 92%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 92%; Pig: 100%; Rabbit: 100%; Rat: 92%
• Image 1: Human 721_B
  
  WB Suggested Anti-TBX3 Antibody Titration: 0.2-1 ug/ml
  ELISA Titer: 1:2500
  Positive Control: 721_B cell lysate
• Image 2: Human
  
  Primary metastatic Melenoma
• Image 3: Human 293T Whole Cell
  
  Host: Rabbit
  Target Name: TBX3
  Sample Tissue: Human 293T Whole Cell
  Antibody Dilution: 1ug/ml