| Product Number |
ARP33314_P050 |
| Product Page |
www.avivasysbio.com/snai1-antibody-n-terminal-region-arp33314-p050.html |
| Name |
SNAI1 Antibody - N-terminal region (ARP33314_P050) |
| Protein Size (# AA) |
264 amino acids |
| Molecular Weight |
29kDa |
| NCBI Gene Id |
6615 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Snail homolog 1 (Drosophila) |
| Alias Symbols |
SNA, SNAH, SNAIL, SLUGH2, SNAIL1, dJ710H13.1 |
| Peptide Sequence |
Synthetic peptide located within the following region: MPRSFLVRKPSDPNRKPNYSELQDSNPEFTFQQPYDQAHLLAAIPPPEIL |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Zhou,B.P., et al., (2004) Nat. Cell Biol. 6 (10), 931-940 |
| Description of Target |
The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. |
| Protein Interactions |
MTUS2; KRT31; TRIM23; ACTN2; MID2; NOTCH2NL; KRTAP10-3; KRT40; FBXL5; EZH2; RNF2; RING1; LATS2; UBC; BTRC; TP53; MDM2; GSK3B; HDAC1; CHD4; KDM1A; HDAC3; HDAC2; RCOR1; FBXL14; NOTCH1; HIST1H3A; EGR1; AJUBA; Sin3a; HOXD4; SUZ12; CTDSP1; CTDSPL; CTDSP2; QRIC |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-SNAI1 (ARP33314_P050) antibody |
| Blocking Peptide |
For anti-SNAI1 (ARP33314_P050) antibody is Catalog # AAP33314 (Previous Catalog # AAPP04356) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human SNAI1 |
| Uniprot ID |
O95863 |
| Protein Name |
Zinc finger protein SNAI1 |
| Publications |
Cooper, C. D. O. et al. Identification and characterization of peripheral T-cell lymphoma-associated SEREX antigens. PLoS One 6, e23916 (2011). 21914172
Surati, M. et al. Proteomic characterization of non-small cell lung cancer in a comprehensive translational thoracic oncology database. J. Clin. Bioinforma. 1, 1-11 (2011). 21603121
Wang, H. et al. PRL-3 down-regulates PTEN expression and signals through PI3K to promote epithelial-mesenchymal transition. Cancer Res. 67, 2922-6 (2007). 17409395 |
| Sample Type Confirmation |
SNAI1 is supported by BioGPS gene expression data to be expressed in 721_B |
| Protein Accession # |
NP_005976 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_005985 |
| Tested Species Reactivity |
Human, Mouse |
| Gene Symbol |
SNAI1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Guinea Pig |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Guinea Pig: 100%; Human: 100%; Mouse: 93%; Rat: 100% |
| Image 1 | Human 721_B
 | WB Suggested Anti-SNAI1 Antibody Titration: 1ug/ml
Positive Control: 721_B cell lysateSNAI1 is supported by BioGPS gene expression data to be expressed in 721_B |
|
| Image 2 | Mouse Spleen
 | Host: Mouse
Target Name: SNAI1
Sample Tissue: Mouse Spleen
Antibody Dilution: 1ug/ml |
|
| Image 3 | Human Urinary Bladder
 | Rabbit Anti-SNAI1 Antibody
Catalog Number: ARP33314_P050
Formalin Fixed Paraffin Embedded Tissue: Human Urinary Bladder Tissue
Observed Staining: Cytoplasm
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec |
|
| Image 4 | Human kidney
 | Human kidney |
|
