| Product Number |
ARP33248_P050 |
| Product Page |
www.avivasysbio.com/rxra-antibody-c-terminal-region-arp33248-p050.html |
| Name |
RXRA Antibody - C-terminal region (ARP33248_P050) |
| Protein Size (# AA) |
462 amino acids |
| Molecular Weight |
51kDa |
| NCBI Gene Id |
6256 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Retinoid X receptor, alpha |
| Alias Symbols |
NR2B1 |
| Peptide Sequence |
Synthetic peptide located within the following region: MDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQ |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Lamhonwah,A.M., (2008) Mol. Cell. Biol. 28 (11), 3817-3829 |
| Description of Target |
Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. RXRA is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators.Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Protein Interactions |
PPARG; VDR; NCOA1; NSD1; UBC; NR1I3; NCOA4; THRB; THRA; ALOX15B; RARA; PPARA; CHD9; PRKD2; NR0B2; STAT1; NR3C2; SMAD2; GK; JAZF1; ACVR1B; NR1I2; NCOA2; PSMC5; RAD54L2; ARID5A; PML; SUMO1; ESR2; ESR1; BHLHE40; BHLHE41; NR4A1; EP300; NCOR1; NCOA6; NCOA3; TR |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-RXRA (ARP33248_P050) antibody |
| Blocking Peptide |
For anti-RXRA (ARP33248_P050) antibody is Catalog # AAP33248 (Previous Catalog # AAPP04285) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human RXRA |
| Uniprot ID |
P19793 |
| Protein Name |
Retinoic acid receptor RXR-alpha |
| Protein Accession # |
NP_002948 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_002957 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
RXRA |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%; Zebrafish: 93% |
| Image 1 | Human Jurkat
 | WB Suggested Anti-RXRA Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysate |
|
