Product Number |
ARP32743_T100 |
Product Page |
www.avivasysbio.com/foxp3-antibody-n-terminal-region-arp32743-t100.html |
Name |
FOXP3 Antibody - N-terminal region (ARP32743_T100) |
Protein Size (# AA) |
431 amino acids |
Molecular Weight |
47kDa |
NCBI Gene Id |
50943 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Forkhead box P3 |
Description |
|
Alias Symbols |
JM2, AIID, IPEX, PIDX, XPID, DIETER |
Peptide Sequence |
Synthetic peptide located within the following region: PHFMHQLSTVDAHARTPVLQVHPLESPAMISLTPPTTATGVFSLKARPGL |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Takahata,Y., et al., (2004) Exp.Hematol.32(7),622-629 |
Description of Target |
Forkhead box protein P3 (FOXP3, Scurfin, Zinc finger protein JM2) encodes a novel member of the forkhead family of transcription factors. It presumably represses transcription, playing a paramount role in determining the amplitude of the response of CD4 T cells to activation |
Protein Interactions |
PRR20A; RBPMS; STUB1; UBC; HSPA1A; IKZF3; GATA3; RUNX1; RELA; NFATC1; HIST1H1B; HDAC1; KAT8; REL; IKZF4; NFAT5; NFATC2; HDAC4; HDAC2; HDAC7; KAT5; HDAC9; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-FOXP3 (ARP32743_T100) antibody |
Blocking Peptide |
For anti-FOXP3 (ARP32743_T100) antibody is Catalog # AAP32743 (Previous Catalog # AAPP03757) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human FOXP3 |
Uniprot ID |
Q9BZS1 |
Protein Name |
Forkhead box protein P3 |
Publications |
Kawabata, A. et al. Naïve rat umbilical cord matrix stem cells significantly attenuate mammary tumor growth through modulation of endogenous immune responses. Cytotherapy 15, 586-97 (2013). 23474329 |
Protein Accession # |
NP_054728 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_014009 |
Tested Species Reactivity |
Human, Mouse |
Gene Symbol |
FOXP3 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 79%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 86%; Rat: 86%; Sheep: 100% |
Image 1 | Mouse spleen
| ?Sample Type: Mouse Spleen frozen with positive lymphocytes/ HPF (x400) Primary Dilution: 1:100 Secondary Antibody: Vector Lab Goat Biotin-Conjugated Anti-Rabbit IgG Secondary Dilution: 1:100 Image Submitted By: Atsushi Kawabata at Kansas State University |
|
Image 2 | Human NCI-H226
| Host: Rabbit Target Name: FOXP3 Sample Tissue: Human NCI-H226 Antibody Dilution: 1.0ug/ml |
|
Image 3 | Human Liver
| Human Liver |
|