| Product Number |
ARP32743_T100 |
| Product Page |
www.avivasysbio.com/foxp3-antibody-n-terminal-region-arp32743-t100.html |
| Name |
FOXP3 Antibody - N-terminal region (ARP32743_T100) |
| Protein Size (# AA) |
431 amino acids |
| Molecular Weight |
47kDa |
| NCBI Gene Id |
50943 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Forkhead box P3 |
| Description |
|
| Alias Symbols |
JM2, AIID, IPEX, PIDX, XPID, DIETER |
| Peptide Sequence |
Synthetic peptide located within the following region: PHFMHQLSTVDAHARTPVLQVHPLESPAMISLTPPTTATGVFSLKARPGL |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Takahata,Y., et al., (2004) Exp.Hematol.32(7),622-629 |
| Description of Target |
Forkhead box protein P3 (FOXP3, Scurfin, Zinc finger protein JM2) encodes a novel member of the forkhead family of transcription factors. It presumably represses transcription, playing a paramount role in determining the amplitude of the response of CD4 T cells to activation |
| Protein Interactions |
PRR20A; RBPMS; STUB1; UBC; HSPA1A; IKZF3; GATA3; RUNX1; RELA; NFATC1; HIST1H1B; HDAC1; KAT8; REL; IKZF4; NFAT5; NFATC2; HDAC4; HDAC2; HDAC7; KAT5; HDAC9; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-FOXP3 (ARP32743_T100) antibody |
| Blocking Peptide |
For anti-FOXP3 (ARP32743_T100) antibody is Catalog # AAP32743 (Previous Catalog # AAPP03757) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human FOXP3 |
| Uniprot ID |
Q9BZS1 |
| Protein Name |
Forkhead box protein P3 |
| Publications |
Kawabata, A. et al. Naïve rat umbilical cord matrix stem cells significantly attenuate mammary tumor growth through modulation of endogenous immune responses. Cytotherapy 15, 586-97 (2013). 23474329 |
| Protein Accession # |
NP_054728 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_014009 |
| Tested Species Reactivity |
Human, Mouse |
| Gene Symbol |
FOXP3 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 79%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 86%; Rat: 86%; Sheep: 100% |
| Image 1 | Mouse spleen
 | ?Sample Type: Mouse Spleen frozen with positive lymphocytes/ HPF (x400)
Primary Dilution: 1:100
Secondary Antibody: Vector Lab Goat Biotin-Conjugated Anti-Rabbit IgG
Secondary Dilution: 1:100
Image Submitted By:
Atsushi Kawabata at Kansas State University |
|
| Image 2 | Human NCI-H226
 | Host: Rabbit
Target Name: FOXP3
Sample Tissue: Human NCI-H226
Antibody Dilution: 1.0ug/ml |
|
| Image 3 | Human Liver
 | Human Liver |
|
