SRC Antibody - N-terminal region (ARP32475_P050)

Data Sheet
 
Product Number ARP32475_P050
Product Page www.avivasysbio.com/src-antibody-n-terminal-region-arp32475-p050.html
Name SRC Antibody - N-terminal region (ARP32475_P050)
Protein Size (# AA) 536 amino acids
Molecular Weight 60kDa
NCBI Gene Id 6714
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
Alias Symbols ASV, SRC1, THC6, c-SRC, p60-Src
Peptide Sequence Synthetic peptide located within the following region: MGSNKSKPKDASQRRRSLEPAENVHGAGGGAFPASQTPSKPASADGHRGP
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Pechkovsky,D.V., (2008) J. Biol. Chem. 283 (19), 12898-12908
Description of Target This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. SRC protein is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Protein Interactions PSMB9; POLR2L; POLR2K; POLR2J; POLR2I; POLR2H; POLR2G; POLR2F; POLR2E; POLR2D; POLR2C; POLR2B; POLR2A; NEDD4; MAPT; ESR1; CA3; ARRB2; UBC; SRC; SPRR2A; IKBKG; CBLC; ZNF658B; TLR4; RGS16; PTGER4; EGFR; ARRB1; TNFRSF1A; KHDRBS1; SYK; CD44; ENO1; ANXA7; PIK3
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-SRC (ARP32475_P050) antibody
Blocking Peptide For anti-SRC (ARP32475_P050) antibody is Catalog # AAP32475 (Previous Catalog # AAPP03474)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human SRC
Uniprot ID P12931
Protein Name Proto-oncogene tyrosine-protein kinase Src
Protein Accession # NP_938033
Purification Affinity Purified
Nucleotide Accession # NM_198291
Tested Species Reactivity Human
Gene Symbol SRC
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 85%; Dog: 92%; Guinea Pig: 92%; Human: 100%; Mouse: 100%; Rabbit: 77%; Rat: 100%
Image 1
Human 293T
WB Suggested Anti-SRC Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: 293T cell lysate
Image 2
human ovarian carcinoma
SRC antibody - N-terminal region (ARP32475_P050) validated by WB using total cell lysate from human ovarian carcinoma cells at 1:1000.
 

AVIVA SYSTEMS BIOLOGY manufactures and sells quality antibody products covering genome wide proteins.

AVIVA SYSTEMS BIOLOGY
10211 Pacific Mesa Blvd, Ste 401, San Diego, CA 92121 USA | Tel: (858)552-6979 | info@avivasysbio.com