CTBP1 Antibody - C-terminal region (ARP32468_P050)

• Product Number: ARP32468_P050
• Name: CTBP1 Antibody - C-terminal region (ARP32468_P050)
• Protein Size (# AA): 440 amino acids
• Molecular Weight: 48kDa
• NCBI Gene Id: 1487
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: C-terminal binding protein 1
• Alias Symbols: BARS, HADDTS
• Peptide Sequence: Synthetic peptide located within the following region: TGIPAAVEGIVPSAMSLSHGLPPVAHPPHAPSPGQTVKPEADRDHASDQL
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Reference: Lin,X., et al., (2003) Mol. Cell. Biol. 23 (24), 9081-9093
• Description of Target: The phosphoprotein C-terminal binding protein 1 (CTBP-1) binds the C-terminus of adenovirus E1A protein. CTBP-1 is a transcriptional repressor and may play a role during cellular proliferation. A second closely related gene, CTBP2, maps to chromosome 21.
• Protein Interactions: CTBP2; CTBP1; CRY2; NOL4L; FOXP2; DMRTB1; TSHZ3; BCAS3; PLCB1; CEP68; KLF12; IKZF1; NOL4; TGIF1; MAPK9; PRKAA1; HOXB5; TCF4; SNRPN; DGCR6; NRIP1; FUNDC1; LNX1; LCOR; RNF111; KLF3; IKZF2; RAI2; ZBTB18; ARNT2; ZEB2; PIAS2; CDC23; LCORL; MARCH10; SMAD6; UBC;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-CTBP1 (ARP32468_P050) antibody is Catalog # AAP32468 (Previous Catalog # AAPP03466)
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CTBP1
• Uniprot ID: Q13363
• Protein Name: C-terminal-binding protein 1
• Publications:

  Anti-CLDN13 ARP32468_P050 has recently been referenced in the following publications:

  Mittal, M. K., Singh, K., Misra, S. & Chaudhuri, G. SLUG-induced elevation of D1 cyclin in breast cancer cells through the inhibition of its ubiquitination. J. Biol. Chem. 286, 469–79 (2011). 21044962

• Sample Type Confirmation:

  CTBP1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

• Protein Accession #: NP_001319
• Purification: Affinity Purified
• Nucleotide Accession #: NM_001328
• Tested Species Reactivity: Human, Mouse
• Gene Symbol: CTBP1
• Predicted Species Reactivity: Human, Mouse, Rat, Dog, Horse, Pig
• Application: WB, IHC
• Predicted Homology Based on Immunogen Sequence: Dog: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 100%; Rat: 100%
• Image 1: Mouse Brain
  
  Host: Mouse
  Target Name: CTBP1
  Sample Tissue: Mouse Brain
  Antibody Dilution: 1ug/ml
• Image 2: Human Jurkat
  
  WB Suggested Anti-CTBP1 Antibody Titration: 0.2-1 ug/ml
  ELISA Titer: 1:62500
  Positive Control: Jurkat cell lysateCTBP1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells
• Image 3: Human Pancreas
  
  Human Pancreas
• Image 4: Human Pineal Tissue
  
  CTBP1 antibody - C-terminal region (ARP32468_P050)
  Catalog Number: ARP32468_P050
  Formalin Fixed Paraffin Embedded Tissue: Human Pineal Tissue
  Observed Staining: Cytoplasm and nucleus in Human Pineal Tissue
  Primary Antibody Concentration: 1:100
  Other Working Concentrations: 1/600
  Secondary Antibody: Donkey anti-Rabbit-Cy3
  Secondary Antibody Concentration: 1:200
  Magnification: 20X
  Exposure Time: 0.5 - 2.0 sec