| Product Number |
ARP32409_T100 |
| Product Page |
www.avivasysbio.com/sirt6-antibody-n-terminal-region-arp32409-t100.html |
| Name |
SIRT6 Antibody - N-terminal region (ARP32409_T100) |
| Protein Size (# AA) |
355 amino acids |
| Molecular Weight |
39kDa |
| NCBI Gene Id |
51548 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Sirtuin 6 |
| Alias Symbols |
SIR2L6 |
| Peptide Sequence |
Synthetic peptide located within the following region: STASGIPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVG |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Frye,R.A., (2000) Biochem Biophys Res Commun. 273(2), 793-8 |
| Description of Target |
SIRT6 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by SIRT6 is included in class IV of the sirtuin family. |
| Protein Interactions |
UBC; MDM2; AKT1; STUB1; SKP2; ABCF2; FAF1; VIM; UBE2D1; CHD3; NR0B2; tat; CCNDBP1; RELA; XRCC5; PRKDC; XRCC6; ELF5; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-SIRT6 (ARP32409_T100) antibody |
| Blocking Peptide |
For anti-SIRT6 (ARP32409_T100) antibody is Catalog # AAP32409 (Previous Catalog # AAPP03404) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human SIRT6 |
| Uniprot ID |
Q8N6T7 |
| Protein Name |
NAD-dependent protein deacetylase sirtuin-6 |
| Protein Accession # |
NP_057623 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_016539 |
| Tested Species Reactivity |
Human, Mouse |
| Gene Symbol |
SIRT6 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 92%; Dog: 100%; Guinea Pig: 93%; Horse: 92%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100% |
| Image 1 | Human HepG2
 | WB Suggested Anti-SIRT6 Antibody Titration: 1.25ug/ml
Positive Control: HepG2 cell lysate |
|
| Image 2 | Human U2OS
 | U2OS |
|
| Image 3 | Mouse Skeletal Muscle
 | Host: Mouse
Target Name: SIRT6
Sample Tissue: Mouse Skeletal Muscle
Antibody Dilution: 1ug/ml |
|
