| Product Number |
ARP32378_T100 |
| Product Page |
www.avivasysbio.com/ruvbl2-antibody-n-terminal-region-arp32378-t100.html |
| Name |
RUVBL2 Antibody - N-terminal region (ARP32378_T100) |
| Protein Size (# AA) |
463 amino acids |
| Molecular Weight |
51kDa |
| NCBI Gene Id |
10856 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
RuvB-like 2 (E. coli) |
| Alias Symbols |
RVB2, TIH2, ECP51, TIP48, CGI-46, ECP-51, INO80J, REPTIN, TIP49B, TAP54-beta |
| Peptide Sequence |
Synthetic peptide located within the following region: IERIGAHSHIRGLGLDDALEPRQASQGMVGQLAARRAAGVVLEMIREGKI |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Bauer,A., et al., (2000) EMBO J.19(22),6121-6130 |
| Description of Target |
RuvB-Like 2 (48-kDa TATA box-binding protein-interacting protein, Reptin 52, RUVBL2) is the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this protein has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation. |
| Protein Interactions |
CCDC103; LNX1; RUVBL1; UBC; DPCD; HUWE1; VCP; SUMO2; RPAP3; MDM2; RPA3; RPA2; RPA1; SUZ12; EED; RNF2; BMI1; CDKN2A; ASNA1; PPP6R3; PLA2G4A; PARK2; FBXO6; TARDBP; YWHAQ; PPP6R2; EXOSC10; BAG3; POLR2E; UPF1; SMG1; RBM8A; TTI1; PAN2; TBP; CTNNB1; STOM; RUVBL |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-RUVBL2 (ARP32378_T100) antibody |
| Blocking Peptide |
For anti-RUVBL2 (ARP32378_T100) antibody is Catalog # AAP32378 (Previous Catalog # AAPP03368) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human RUVBL2 |
| Uniprot ID |
Q9Y230 |
| Protein Name |
RuvB-like 2 |
| Sample Type Confirmation |
RUVBL2 is supported by BioGPS gene expression data to be expressed in Daudi |
| Protein Accession # |
NP_006657 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_006666 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
RUVBL2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 79%; Zebrafish: 93% |
| Image 1 | siRUVBL2 transfected H1299
 | Sample Type:
Lane 1: 20ug untransfected H1299 cells Lane 2: 20ug siRUVBL2 transfected H1299 cells Primary Antibody Dilution:
1:1000 Secondary Antibody:
Anti-rabbit-HRP Secondary Antibody Dilution:
1:3000 Color/Signal Descriptions:
RUVBL2 Gene Name:
Wenwei Hu, Xuetian Yue, Rutgers Cancer Institute of New Jersey. Submitted by:
|
|
| Image 2 | Human Daudi
 | WB Suggested Anti-RUVBL2 Antibody Titration: 2.0-4.0ug/ml
Positive Control: Daudi cell lysateRUVBL2 is supported by BioGPS gene expression data to be expressed in Daudi |
|
| Image 3 | Human Lung
 | Human Lung |
|
| Image 4 | Human urinary bladder
 | Human urinary bladder |
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