| Product Number |
ARP32243_T100 |
| Product Page |
www.avivasysbio.com/ahr-antibody-n-terminal-region-arp32243-t100.html |
| Name |
AHR Antibody - N-terminal region (ARP32243_T100) |
| Protein Size (# AA) |
848 amino acids |
| Molecular Weight |
96kDa |
| NCBI Gene Id |
196 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Aryl hydrocarbon receptor |
| Description |
|
| Alias Symbols |
RP85, bHLHe76 |
| Peptide Sequence |
Synthetic peptide located within the following region: RAKSFFDVALKSSPTERNGGQDNCRAANFREGLNLQEGEFLLQALNGFVL |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Schwabe,J.W., et al., (2006) Cell. Signal. 18 (5), 740-750 |
| Description of Target |
AHR is a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Its ligands included a variety of aromatic hydrocarbons. |
| Protein Interactions |
GNA13; UBC; NFE2L2; MAF; RB1; EP300; ARNT; NCOA2; NCOA1; TBP; TAF9; TAF6; TAF4; NCOA7; NCOR2; BRCA1; IVNS1ABP; AIP; STUB1; AHR; FOXA1; SUMO2; DDB1; CTNNB1; TAF7; PTGES3; SMARCA4; NEDD8; XPO1; ARNTL; CCNT1; NRIP1; DAP3; AR; CUL4B; GTF2F2; RELA; HSP90AA1; E |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-AHR (ARP32243_T100) antibody |
| Blocking Peptide |
For anti-AHR (ARP32243_T100) antibody is Catalog # AAP32243 (Previous Catalog # AAPP03224) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human AHR |
| Uniprot ID |
P35869 |
| Protein Name |
Aryl hydrocarbon receptor |
| Publications |
The AhR Ligand, TCDD, Regulates Androgen Receptor Activity Differently in Androgen-Sensitive versus Castration-Resistant Human Prostate Cancer Cells. Int J Environ Res Public Health. 12, 7506-18 (2015). 26154658 |
| Protein Accession # |
NP_001612 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_001621 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
AHR |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Sheep |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 86%; Dog: 86%; Guinea Pig: 93%; Human: 100%; Mouse: 86%; Rabbit: 79%; Rat: 86%; Sheep: 86% |
| Image 1 | Human kidney
 | Human kidney |
|
| Image 2 | Human HepG2
 | WB Suggested Anti-AHR Antibody Titration: 2.5ug/ml
Positive Control: HepG2 cell lysate |
|
| Image 3 | HepG2
 | Host: Rabbit
Target Name: AHR
Sample Type: HepG2
Lane A: Primary Antibody
Lane B: Primary Antibody + Blocking Peptide
Primary Antibody Concentration: 5.0ug/mL
Peptide Concentration: 2.0ug/mL
Lysate Quantity: 25ug/lane
Gel Concentration: 6%-18% |
|
