| Product Number |
ARP32117_T100 |
| Product Page |
www.avivasysbio.com/pik3cb-antibody-c-terminal-region-arp32117-t100.html |
| Name |
PIK3CB Antibody - C-terminal region (ARP32117_T100) |
| Protein Size (# AA) |
1070 amino acids |
| Molecular Weight |
123kDa |
| Subunit |
beta isoform |
| NCBI Gene Id |
5291 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Phosphoinositide-3-kinase, catalytic, beta polypeptide |
| Alias Symbols |
PI3K, PIK3C1, P110BETA, PI3KBETA |
| Peptide Sequence |
Synthetic peptide located within the following region: VKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKD |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Zhao,J.J., et al., (2005) Proc. Natl. Acad. Sci. U.S.A. 102 (51), 18443-18448 |
| Description of Target |
Phosphoinositide 3-kinases (PI3Ks) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids. They have been implicated as participants in signaling pathways regulating cell growth by virtue of their activation in response to various mitogenic stimuli. PI3Ks are composed of a 110-kD catalytic subunit, such as PIK3CB, and an 85-kD adaptor subunit (Hu et al., 1993).[supplied by OMIM]. |
| Protein Interactions |
EGFR; IRS1; GRB2; PIK3R1; GAB2; PIK3R2; CRK; CBL; RAB5A; UBC; ALAS1; HPS6; DVL3; ALK; AGTR2; PRKCD; PRKCE; YWHAQ; HCK; MME; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-PIK3CB (ARP32117_T100) antibody |
| Blocking Peptide |
For anti-PIK3CB (ARP32117_T100) antibody is Catalog # AAP32117 (Previous Catalog # AAPP03034) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human PIK3CB |
| Uniprot ID |
Q24JU2 |
| Protein Name |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform |
| Protein Accession # |
NP_006210 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_006219 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
PIK3CB |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
| Image 1 | Human Brain
 | WB Suggested Anti-PIK3CB Antibody Titration: 5ug/ml
Positive Control: Human brain |
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