| Product Number |
ARP32008_T100 |
| Product Page |
www.avivasysbio.com/smad7-antibody-n-terminal-region-arp32008-t100.html |
| Name |
SMAD7 Antibody - N-terminal region (ARP32008_T100) |
| Protein Size (# AA) |
426 amino acids |
| Molecular Weight |
46kDa |
| NCBI Gene Id |
4092 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
SMAD family member 7 |
| Alias Symbols |
CRCS3, MADH7, MADH8 |
| Peptide Sequence |
Synthetic peptide located within the following region: LVRRLWRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRA |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Suh,Y.A., (2006) Biochem. Biophys. Res. Commun. 341 (3), 889-894 |
| Description of Target |
Smad7 acts to functionally inactivate RB and de-repress E2F without blocking the activation of TbetaRI and the nuclear translocation of Smad2/3, allowing TGF-beta1 to exert effects in a cancer cell that is resistant to TGF-beta1-mediated growth inhibition. |
| Protein Interactions |
HDAC3; HDAC2; USP11; SMURF2; SMURF1; SKP2; MYC; Melk; HCVgp1; RNF111; KDM2A; SOX13; PIAS1; SOX7; UBE2O; MKL2; ASH1L; PIAS4; CXXC5; ZNF107; ZBTB11; HEYL; TTF2; UBC; TTF1; SOX5; MYOD1; XRCC6; CTNNB1; MAPK14; BAMBI; PPP1R15A; NEDD4L; STAMBP; YAP1; AXIN1; TP5 |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-SMAD7 (ARP32008_T100) antibody |
| Blocking Peptide |
For anti-SMAD7 (ARP32008_T100) antibody is Catalog # AAP32008 (Previous Catalog # AAPP02909) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human SMAD7 |
| Uniprot ID |
O15105 |
| Protein Name |
Mothers against decapentaplegic homolog 7 |
| Protein Accession # |
NP_005895 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_005904 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
SMAD7 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Pig, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 93%; Human: 100%; Mouse: 92%; Pig: 93%; Rabbit: 93%; Rat: 85% |
| Image 1 | Human Lung
 | Host: Rabbit
Target Name: SMAD7
Sample Type: Human Lung
Antibody Dilution: 1.0 ug/ml |
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