| Product Number |
ARP31964_P050 |
| Product Page |
www.avivasysbio.com/hoxd3-antibody-middle-region-arp31964-p050.html |
| Name |
HOXD3 Antibody - middle region (ARP31964_P050) |
| Protein Size (# AA) |
432 amino acids |
| Molecular Weight |
46kDa |
| NCBI Gene Id |
3232 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Homeobox D3 |
| Alias Symbols |
HOX4, HOX1D, HOX4A, Hox-4.1 |
| Peptide Sequence |
Synthetic peptide located within the following region: AHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPPPPPPTLPPS |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
HOXD3 (homeobox D3) belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that remove the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. HOXD3 may play a role in the regulation of cell adhesion processes. |
| Protein Interactions |
Hoxa1; ALX4; DDB1; HMGB1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-HOXD3 (ARP31964_P050) antibody |
| Blocking Peptide |
For anti-HOXD3 (ARP31964_P050) antibody is Catalog # AAP31964 (Previous Catalog # AAPP02861) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human HOXD3 |
| Uniprot ID |
P31249 |
| Protein Name |
Homeobox protein Hox-D3 |
| Publications |
Kodama, A. et al. Establishment of canine hemangiosarcoma xenograft models expressing endothelial growth factors, their receptors, and angiogenesis-associated homeobox genes. BMC Cancer 9, 363 (2009). 19825192
Kodama, A. et al. Immunohistochemical demonstration of angiogenesis-associated homeobox proteins in canine vascular tumours. J. Comp. Pathol. 141, 199-203 19505696 |
| Protein Accession # |
NP_008829 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_006898 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
HOXD3 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 100% |
| Image 1 | Human Jurkat
 | WB Suggested Anti-HOXD3 Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysate |
|
