HOXA13 Antibody - middle region : FITC (ARP31955_P050-FITC)

• Product Number: ARP31955_P050-FITC
• Name: HOXA13 Antibody - middle region : FITC (ARP31955_P050-FITC)
• Protein Size (# AA): 388 amino acids
• Molecular Weight: 40kDa
• Conjugation: FITC: Fluorescein Isothiocyanate
• NCBI Gene Id: 3209
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: Homeobox A13
• Alias Symbols: HOX1, HOX1J
• Peptide Sequence: Synthetic peptide located within the following region: AAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAA
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer.
• Description of Target: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome.
• Protein Interactions: UBC; MEIS3; SMAD5; MEIS2; MEIS1; SMAD1; SMAD2;
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Blocking Peptide: For anti-HOXA13 (ARP31955_P050-FITC) antibody is Catalog # AAPY04304
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HOXA13
• Uniprot ID: P31271
• Protein Name: Homeobox protein Hox-A13
• Publications:

  Villavicencio-Lorini, P. et al. Homeobox genes d11-d13 and a13 control mouse autopod cortical bone and joint formation. J. Clin. Invest. 120, 1994-2004 (2010). WB, IHC, Human, Mouse, Dog 20458143

• Protein Accession #: NP_000513
• Purification: Affinity Purified
• Nucleotide Accession #: NM_000522
• Gene Symbol: HOXA13
• Predicted Species Reactivity: Human, Mouse, Dog
• Application: WB
• Predicted Homology Based on Immunogen Sequence: Dog: 83%; Human: 100%; Mouse: 92%
• Image 1: