| Product Number |
ARP31688_P050 |
| Product Page |
www.avivasysbio.com/atf6-antibody-n-terminal-region-arp31688-p050.html |
| Name |
ATF6 Antibody - N-terminal region (ARP31688_P050) |
| Protein Size (# AA) |
670 amino acids |
| Molecular Weight |
74kDa |
| NCBI Gene Id |
22926 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Activating transcription factor 6 |
| Description |
|
| Alias Symbols |
ACHM7, ATF6A |
| Peptide Sequence |
Synthetic peptide located within the following region: GYFTDTDELQLEAANETYENNFDNLDFDLDLMPWESDIWDINNQICTVKD |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Kerbiriou,M., Biochim. Biophys. Acta 1772 (11-12), 1236-1249 (2007) |
| Description of Target |
ATF6 is an endoplasmic reticulum (ER) stress-regulated transmembrane transcription factor that activates the transcription of ER molecules.ATF6 is an endoplasmic reticulum (ER) stress-regulated transmembrane transcription factor that activates the transcription of ER molecules.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-171 AB015856.1 2-172 172-265 BC014969.1 124-217 266-336 AB015856.1 267-337 337-650 BC014969.1 289-602 651-1294 AF005887.1 626-1269 1295-2406 AB015856.1 1296-2407 2407-2488 AF005887.1 2375-2456 |
| Protein Interactions |
UBC; MAPK14; FBXO6; ATF6; XBP1; NNMT; DDC; BPGM; TNFRSF1A; APP; SP1; SUMO2; SYVN1; WFS1; SREBF2; YY1; NFYC; CREB1; CREB3L3; GTF2I; ATF6B; SRF; NFYA; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-ATF6 (ARP31688_P050) antibody |
| Blocking Peptide |
For anti-ATF6 (ARP31688_P050) antibody is Catalog # AAP31688 (Previous Catalog # AAPP02475) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human ATF6 |
| Uniprot ID |
P18850 |
| Protein Name |
Cyclic AMP-dependent transcription factor ATF-6 alpha |
| Publications |
Exclusion of the unfolded protein response in light-induced retinal degeneration in the canine T4R RHO model of autosomal dominant retinitis pigmentosa. PLoS One. 10, e0115723 (2015). 25695253
Protein kinase R-like endoplasmatic reticulum kinase is a mediator of stretch in ventilator-induced lung injury. Respir Res. 19, 157 (2018). 30134920 |
| Sample Type Confirmation |
ATF6 is supported by BioGPS gene expression data to be expressed in HeLa |
| Protein Accession # |
NP_031374 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_007348 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
ATF6 |
| Predicted Species Reactivity |
Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 86%; Dog: 79%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Rabbit: 92%; Rat: 79% |
| Image 1 | Human HeLa
 | WB Suggested Anti-ATF6 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Hela cell lysateATF6 is supported by BioGPS gene expression data to be expressed in HeLa |
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