Product Number |
ARP31635_T100 |
Product Page |
www.avivasysbio.com/ahr-antibody-n-terminal-region-arp31635-t100.html |
Name |
AHR Antibody - N-terminal region (ARP31635_T100) |
Protein Size (# AA) |
848 amino acids |
Molecular Weight |
96kDa |
NCBI Gene Id |
196 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Aryl hydrocarbon receptor |
Alias Symbols |
RP85, bHLHe76 |
Peptide Sequence |
Synthetic peptide located within the following region: MNSSSANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRL |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Marlowe,J.L., et al., (2004) J. Biol. Chem. 279 (28), 29013-29022 |
Description of Target |
Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. AHR has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. AHR ligands included a variety of aromatic hydrocarbons. |
Protein Interactions |
GNA13; UBC; NFE2L2; MAF; RB1; EP300; ARNT; NCOA2; NCOA1; TBP; TAF9; TAF6; TAF4; NCOA7; NCOR2; BRCA1; IVNS1ABP; AIP; STUB1; AHR; FOXA1; SUMO2; DDB1; CTNNB1; TAF7; PTGES3; SMARCA4; NEDD8; XPO1; ARNTL; CCNT1; NRIP1; DAP3; AR; CUL4B; GTF2F2; RELA; HSP90AA1; E |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-AHR (ARP31635_T100) antibody |
Blocking Peptide |
For anti-AHR (ARP31635_T100) antibody is Catalog # AAP31635 (Previous Catalog # AAPP02422) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human AHR |
Uniprot ID |
P35869 |
Protein Name |
Aryl hydrocarbon receptor |
Protein Accession # |
NP_001612 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_001621 |
Tested Species Reactivity |
Human |
Gene Symbol |
AHR |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
Image 1 | Human HepG2
| Lanes: Lane1: 50 ug HepG2 nuclei extract + benzo[a]pyrene Lane2: 50 ug HepG2 cytoplasm extract + benzo[a]pyrene Primary Antibody Dilution: 1:1000 Secondary Antibody: Anti-rabbit HRP Secondary Antibody Dilution: 1:1000 Gene Name: AHR (Arylhydrocarbon receptor) Submitted by: Anonymous
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Image 2 | Human HepG2
| AHR antibody - N-terminal region (ARP31635_T100) validated by WB using Human HepG2 Lysate at 2.5ug/ml, 5ug/ml. |
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Image 3 | Human Placenta
| WB Suggested Anti-AHR Antibody Titration: 2.5ug/ml ELISA Titer: 1:12500 Positive Control: Human Placenta |
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Image 4 | Human Urinary Bladder
| Rabbit Anti-AHR Antibody Catalog Number: ARP31635_T100 Formalin Fixed Paraffin Embedded Tissue: Human Urinary Bladder Tissue Observed Staining: Cytoplasm Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec |
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Image 5 | A549, THP-1
| Host: Rabbit Target: AHR Positive control (+): A549 (N03) Negative control (-): THP-1 (N30) Antibody concentration: 5ug/ml |
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Image 6 | Human U937 Whole Cell
| Host: Rabbit Target Name: AHR Sample Tissue: Human U937 Whole Cell Antibody Dilution: 1ug/ml |
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