Product Number |
ARP31476_P050 |
Product Page |
www.avivasysbio.com/cdx2-antibody-middle-region-arp31476-p050.html |
Name |
CDX2 Antibody - middle region (ARP31476_P050) |
Protein Size (# AA) |
313 amino acids |
Molecular Weight |
34 kDa |
NCBI Gene Id |
1045 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Caudal type homeobox 2 |
Alias Symbols |
CDX3, CDX-3, CDX2/AS |
Peptide Sequence |
Synthetic peptide located within the following region: QRRNLCEWMRKPAQQSLGSQVKTRTKDKYRVVYTDHQRLELEKEFHYSRY |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Saad,R.S., et al., (2004) J. Clin. Pathol. 122 (3), 421-427 |
Description of Target |
CDX2 encodes a protein that plays an important role in gallbladder carcinogenesis with intestinal differentiation. Cdx2 is a highly sensitive marker for Barrett's esophagus. |
Protein Interactions |
CDK2; SMARCD1; SMARCB1; SMARCA4; SMARCA2; KDM5B; UBB; PAX6; GSK3B; EP300; CDX2; MAPK14; CREBBP; MAPK1; HNF1A; ACAT2; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Enhanced Validation |
Relative Expression (Western Blot) |
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Datasheets/Manuals |
Printable datasheet for anti-CDX2 (ARP31476_P050) antibody |
Blocking Peptide |
For anti-CDX2 (ARP31476_P050) antibody is Catalog # AAP31476 (Previous Catalog # AAPP02238) |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human CDX2 |
Uniprot ID |
Q99626 |
Protein Name |
Homeobox protein CDX-2 |
Publications |
Tajbakhsh, J. Covisualization of methylcytosine, global DNA, and protein biomarkers for In Situ 3D DNA methylation phenotyping of stem cells. Methods Mol. Biol. 1052, 77-88 (2013). 23593143 |
Protein Accession # |
NP_001256 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_001265 |
Tested Species Reactivity |
Human, Mouse |
Gene Symbol |
CDX2 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 91%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
Image 1 | Human Brain
| WB Suggested Anti-CDX2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human brain |
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Image 2 | Mouse Skeletal Muscle
| Host: Mouse Target Name: CDX2 Sample Tissue: Mouse Skeletal Muscle Antibody Dilution: 1ug/ml |
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Image 3 |
| 25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 0.5 ug/mL of the antibody was used in this experiment. The protein may be modified by phosphorylation.
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