Product Number |
ARP31464_P050 |
Product Page |
www.avivasysbio.com/olig2-antibody-n-terminal-region-arp31464-p050.html |
Name |
OLIG2 Antibody - N-terminal region (ARP31464_P050) |
Protein Size (# AA) |
323 amino acids |
Molecular Weight |
32kDa |
NCBI Gene Id |
10215 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Oligodendrocyte lineage transcription factor 2 |
Alias Symbols |
BHLHB1, OLIGO2, RACK17, PRKCBP2, bHLHe19 |
Peptide Sequence |
Synthetic peptide located within the following region: MDSDASLVSSRPSSPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPE |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Mitkus,S.N., Schizophr. Res. 98 (1-3), 129-138 (2008) |
Description of Target |
OLIG2 is a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. OLIG2 is an essential regulator of ventral neuroectodermal progenitor cell fate. It is associated with T-cell acute lymphoblastic leukemia due to a chromosomal translocation t(14;21)(q11.2;q22). OLIG2 might play a role in learning deficits associated with Down syndrome.This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Protein Interactions |
CUL3; SRRM1; SOX8; NKX2-2; EP300; SOX10; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-OLIG2 (ARP31464_P050) antibody |
Blocking Peptide |
For anti-OLIG2 (ARP31464_P050) antibody is Catalog # AAP31464 (Previous Catalog # AAPS08403) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human OLIG2 |
Uniprot ID |
Q13516 |
Protein Name |
Oligodendrocyte transcription factor 2 |
Protein Accession # |
NP_005797 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_005806 |
Tested Species Reactivity |
Human |
Gene Symbol |
OLIG2 |
Predicted Species Reactivity |
Human, Mouse, Rat, Dog, Guinea Pig, Horse, Zebrafish |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 85% |
Image 1 | Human 293T
| WB Suggested Anti-OLIG2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Transfected 293T |
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Image 2 | human LCL and mouse brains
| Sample Type: Human Optic Nerve and Spinal CordCellular Target: Oligoden Drocyte Lineage Cells Dilution: 1:500 |
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Image 3 | human LCL and mouse brains
| OLIG2 antibody - N-terminal region (ARP31464_P050) validated by WB using human LCL and mouse brains at 1:1000. |
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