Product Number |
ARP31428_P050 |
Product Page |
www.avivasysbio.com/tal1-antibody-n-terminal-region-arp31428-p050.html |
Name |
TAL1 Antibody - N-terminal region (ARP31428_P050) |
Protein Size (# AA) |
331 amino acids |
Molecular Weight |
34kDa |
NCBI Gene Id |
6886 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
T-cell acute lymphocytic leukemia 1 |
Alias Symbols |
SCL, TCL5, tal-1, bHLHa17 |
Peptide Sequence |
Synthetic peptide located within the following region: TERPPSEAARSDPQLEGRDAAEASMAPPHLVLLNGVAKETSRAAAAEPPV |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Zhang,M. (2008) J. Biol. Chem. 283 (11), 6717-6727 |
Description of Target |
TAL1 is implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. It also serves as a positive regulator of erythroid differentiation |
Protein Interactions |
ELSPBP1; SIN3A; KAT2B; EP300; HOXB9; DRG1; CHD3; ZHX1; STUB1; UBC; RB1; SSBP2; SSBP3; RCOR1; KDM1A; LDB1; TCF12; TCF3; RBBP7; LYL1; HDAC2; HDAC1; CHD4; CBFA2T3; RUNX1; SUPT16H; TAL1; CDK9; TRIM33; SUV39H1; SATB1; TRIM27; NCAPG2; MAPK3; SP1; LMO1; LMO2; GA |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-TAL1 (ARP31428_P050) antibody |
Blocking Peptide |
For anti-TAL1 (ARP31428_P050) antibody is Catalog # AAP31428 (Previous Catalog # AAPP03106) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human TAL1 |
Uniprot ID |
P17542 |
Protein Name |
T-cell acute lymphocytic leukemia protein 1 |
Publications |
Hosur, V. et al. Retrotransposon insertion in the T-cell acute lymphocytic leukemia 1 (Tal1) gene is associated with severe renal disease and patchy alopecia in Hairpatches (Hpt) mice. PLoS One 8, e53426 (2013). 23301070 |
Protein Accession # |
NP_003180 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_003189 |
Tested Species Reactivity |
Human |
Gene Symbol |
TAL1 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Pig, Rabbit |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 85%; Dog: 85%; Human: 100%; Mouse: 92%; Pig: 92%; Rabbit: 92%; Rat: 85% |
Image 1 | Human Fetal Liver
| Host: Rabbit Target Name: TAL1 Sample Type: Human Fetal Liver Antibody Dilution: 1.0ug/ml |
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Image 2 | Human Brain
| WB Suggested Anti-TAL1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Human brain |
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