Product Number |
ARP31262_P050 |
Product Page |
www.avivasysbio.com/nfyb-antibody-middle-region-arp31262-p050.html |
Name |
NFYB Antibody - middle region (ARP31262_P050) |
Protein Size (# AA) |
207 amino acids |
Molecular Weight |
23kDa |
NCBI Gene Id |
4801 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Nuclear transcription factor Y, beta |
Alias Symbols |
HAP3, CBF-A, CBF-B, NF-YB |
Peptide Sequence |
Synthetic peptide located within the following region: EAMKGEKGIGGAVTATDGLSEELTEEAFTNQLPAGLITTDGQQQNVMVYT |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Description of Target |
NFYB is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. |
Protein Interactions |
AGTRAP; POLE4; DRAP1; NFYA; LYN; CDK2; CCNE1; CCNA2; TP53; SMYD3; NFYC; MAOB; UBC; CREBBP; SP1; HDAC1; EP300; KAT2B; TP73; TAF12; TAF11; TAF6; GRB2; YBX3; CEBPZ; C1QBP; TBP; CIITA; CNTN2; MYC; ELF1; YBX1; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-NFYB (ARP31262_P050) antibody |
Blocking Peptide |
For anti-NFYB (ARP31262_P050) antibody is Catalog # AAP31262 (Previous Catalog # AAPP24048) |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human NFYB |
Uniprot ID |
P25208 |
Protein Name |
Nuclear transcription factor Y subunit beta |
Protein Accession # |
NP_006157 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_006166 |
Tested Species Reactivity |
Human |
Gene Symbol |
NFYB |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Yeast |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 100%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Yeast: 91% |
Image 1 | Transfected 293T
| WB Suggested Anti-NFYB Antibody Titration: 0.2-1 ug/ml Positive Control: Transfected 293T |
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