||STAT6 Antibody - C-terminal region (ARP31048_P050)
||D12S1644, IL-4-STAT, STAT6B, STAT6C
|Protein Size (# AA)
||847 amino acids
||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
|NCBI Gene Id
||Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
|Official Gene Full Name
||Signal transducer and activator of transcription 6, interleukin-4 induced
||Synthetic peptide located within the following region: NLYPKKPKDEAFRSHYKPEQMGKDGRGYVPATIKMTVERDQPLPTPELQM
||Li,B.H., (2008) Biochem. Biophys. Res. Commun. 369 (2), 554-560
|Description of Target
||Full-length human STAR6 (NP_003144) was expressed in E.coli as inclusion body and purified after protein refolding for mouse immunization. Clone 5B1 shows excellent western blot detection of endogenous STAT6 using ACHN cell lysate.The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
||UBC; IRF4; PDE12; EHD1; USP8; API5; PGGT1B; EP300; TRIM28; JAK3; RCN3; LITAF; IL4R; EEF1A1; VKORC1; PTPN2; STAT2; JAK1; IFNG; IFNAR1; SRXN1; PSAT1; DSTN; SEC24A; AHCYL1; SSSCA1; NUBP2; SH3BGRL; RAD23B; PPM1G; IGBP1; CEBPE; SND1; SUMO2; FCER2; SFPQ; IGHE;
|Reconstitution and Storage
||For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
See our General FAQ page.
||Printable datasheet for anti-STAT6 (ARP31048_P050) antibody
The following related protocols are available on www.avivasysbio.com
||IHC Information: Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
IHC Information: Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
IHC Information: Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
IHC Information: Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
||Domestic: within 1-2 days delivery International: 1-2 days
||For anti-STAT6 (ARP31048_P050) antibody is Catalog # AAP31048 (Previous Catalog # AAPP24027)
||The immunogen is a synthetic peptide directed towards the C terminal region of human STAT6
|Complete computational species homology data
||Find tissues and cell lines supported by DNA array analysis to express STAT6.
||Signal transducer and activator of transcription 6
|Sample Type Confirmation
STAT6 is strongly supported by BioGPS gene expression data to be expressed in HeLa
|Protein Accession #
||Find tissues and cell lines supported by RNA-seq analysis to express STAT6.
|Nucleotide Accession #
||This antibody may replace item sc-117401 from Santa Cruz Biotechnology.
|Tested Species Reactivity
|Predicted Species Reactivity
||Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
|Predicted Homology Based on Immunogen Sequence
||Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
|Human Tonsil||Human Tonsil|
|Human Testis||Human Testis|
|Human Prostate||Human Prostate|
|Human Kidney||Human Kidney|
|Human HeLa||WB Suggested Anti-STAT6 Antibody Titration: 1 ug/ml|
Positive Control: Hela cell lysateSTAT6 is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells
|Human Lung Tissue||STAT6 antibody - C-terminal region (ARP31048_P050)|
Catalog Number: ARP31048_P050
Formalin Fixed Paraffin Embedded Tissue: Human Lung Tissue
Observed Staining: Cytoplasm of pneumocytes
Primary Antibody Concentration: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Exposure Time: 0.5 - 2.0 sec