| Product Number |
ARP30544_T100 |
| Product Page |
www.avivasysbio.com/map2k4-antibody-c-terminal-region-arp30544-t100.html |
| Name |
MAP2K4 Antibody - C-terminal region (ARP30544_T100) |
| Protein Size (# AA) |
399 amino acids |
| Molecular Weight |
44kDa |
| NCBI Gene Id |
6416 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Alias Symbols |
JNKK, MEK4, MKK4, SEK1, SKK1, JNKK1, SERK1, MAPKK4, PRKMK4, SAPKK1, SAPKK-1 |
| Peptide Sequence |
Synthetic peptide located within the following region: NLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMA |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. |
| Protein Interactions |
UBC; EGFR; GEMIN5; MAP3K5; MAP3K1; GCH1; MAPK10; MAPK9; MAPK8; MAPK1; ARRB2; ARRB1; MAP3K7; RBBP8; JUN; MAP2K7; APP; MAP3K2; MAPK14; AKT1; LRRK2; MAP2K4; MAP2K6; MAP3K4; MAP3K3; PML; BLNK; ITCH; MAPK8IP3; ZAK; SPAG9; TRIB1; MAP3K14; CFLAR; MAPK12; EFNA4; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-MAP2K4 (ARP30544_T100) antibody |
| Blocking Peptide |
For anti-MAP2K4 (ARP30544_T100) antibody is Catalog # AAP30544 |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C-terminal region of Human MAP2K4 |
| Uniprot ID |
P45985 |
| Protein Accession # |
NP_003001 |
| Nucleotide Accession # |
NM_003010 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
MAP2K4 |
| Predicted Species Reactivity |
Human |
| Application |
WB |
| Image 1 | Human COLO205 Whole Cell
 | Host: Rabbit
Target Name: MAP2K4
Sample Tissue: Human COLO205 Whole Cell
Antibody Dilution: 1ug/ml |
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