| Product Number |
ARP30384_T100-FITC |
| Product Page |
www.avivasysbio.com/nbn-antibody-middle-region-fitc-arp30384-t100-fitc.html |
| Name |
NBN Antibody - middle region : FITC (ARP30384_T100-FITC) |
| Protein Size (# AA) |
754 amino acids |
| Molecular Weight |
85kDa |
| Conjugation |
FITC: Fluorescein Isothiocyanate |
| NCBI Gene Id |
4683 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Alias Symbols |
ATV, NBS, P95, NBS1, AT-V1, AT-V2 |
| Peptide Sequence |
Synthetic peptide located within the following region: TGLKTTTPGPSLSQGVSVDEKLMPSAPVNTTTYVADTESEQADTWDLSER |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
| Description of Target |
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. |
| Protein Interactions |
ATRX; RPA3; RPA2; RPA1; EP300; CBX8; UBE2N; UBE2D1; UBC; NCL; H2AFX; RNF8; MDC1; TERF2; MRE11A; TERF2IP; RAD50; TLK1; DCLRE1C; RBBP8; BRCA1; MDM2; CCNE1; SKP2; ATM; ATRIP; XRCC5; PRKDC; LIG3; IPO5; HSPA4; ATR; UBE2A; BARD1; BACH1; RAD18; CD3EAP; UBE2B; WR |
| Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Datasheets/Manuals |
Printable datasheet for anti-NBN (ARP30384_T100-FITC) antibody |
| Blocking Peptide |
For anti-NBN (ARP30384_T100-FITC) antibody is Catalog # AAP30384 |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of Human NBN |
| Uniprot ID |
O60934 |
| Gene Symbol |
NBN |
| Predicted Species Reactivity |
Human |
| Application |
WB |
| Image 1 | |
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