TAF15 Antibody - N-terminal region (ARP30112_P050)

Data Sheet
 
Product Number ARP30112_P050
Product Page www.avivasysbio.com/taf15-antibody-n-terminal-region-arp30112-p050.html
Name TAF15 Antibody - N-terminal region (ARP30112_P050)
Protein Size (# AA) 592 amino acids
Molecular Weight 61kDa
NCBI Gene Id 8148
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
Alias Symbols Npl3, RBP56, TAF2N, TAFII68
Peptide Sequence Synthetic peptide located within the following region: TDSSYGQNYSGYSSYGQSQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQN
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Lee, H.J., et al., (2004) FEBS Lett. 564 (1-2), 188-198
Description of Target Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. Its gene encodes a subunit of TFIID present in a subset of TFIID complexes. Translocations involving chromosome 17 and chromosome 9, where the gene for the nuclear receptor CSMF is located, result in a gene fusion product that is an RNA binding protein associated with a subset of extraskeletal myxoid chondrosarcomas.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a subunit of TFIID present in a subset of TFIID complexes. Translocations involving chromosome 17 and chromosome 9, where the gene for the nuclear receptor CSMF is located, result in a gene fusion product that is an RNA binding protein associated with a subset of extraskeletal myxoid chondrosarcomas. Two transcripts encoding different isoforms have been identified.
Protein Interactions RPA3; RPA2; RPA1; SUZ12; RNF2; EZH2; BMI1; EED; UBD; PRMT8; MED26; UBC; FUS; TPR; TPM2; DDB1; SCARB2; RNF168; TMED9; SAP30BP; NEDD8; CAND1; DCUN1D1; COPS5; COPS6; CUL1; CUL2; CUL3; CUL4A; CUL4B; CUL5; YWHAZ; SIRT7; HIST2H4A; HIST1H3A; HIST2H2AC; CACNA1A;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-TAF15 (ARP30112_P050) antibody
Blocking Peptide For anti-TAF15 (ARP30112_P050) antibody is Catalog # AAP30112 (Previous Catalog # AAPH00288)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human TAF15
Uniprot ID Q92804-2
Protein Name TATA-binding protein-associated factor 2N
Publications

Ko, S. Y., Lengyel, E. & Naora, H. The Müllerian HOXA10 gene promotes growth of ovarian surface epithelial cells by stimulating epithelial-stromal interactions. Mol. Cell. Endocrinol. 317, 112-9 (2010). 20048082

Sample Type Confirmation

TAF15 is supported by BioGPS gene expression data to be expressed in Daudi

Protein Accession # NP_631961
Purification Affinity Purified
Nucleotide Accession # NM_139215
Tested Species Reactivity Human
Gene Symbol TAF15
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Yeast
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 93%; Dog: 93%; Guinea Pig: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Yeast: 77%
Image 1
Human Heart
Rabbit Anti-TAF15 Antibody
Catalog Number: ARP30112
Paraffin Embedded Tissue: Human cardiac cell
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
Image 2
Human Brain
Rabbit Anti-TAF15 Antibody
Catalog Number: ARP30112
Paraffin Embedded Tissue: Human neural cell
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
Image 3
Human 293T
Host: Rabbit
Target Name: TAF15
Sample Tissue: Human 293T
Antibody Dilution: 1.0ug/ml
Image 4
Human Skeletal Muscle
Rabbit Anti-TAF 15 Antibody
Catalog Number: ARP30112
Paraffin Embedded Tissue: Human Skeletal Muscle
Cellular Data: Skeletal muscle cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
Image 5
Human kidney
Rabbit Anti-TAF 15 Antibody
Catalog Number: ARP30112
Paraffin Embedded Tissue: Human Kidney
Cellular Data: Epithelial cells of collecting tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
 

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