| Product Number |
ARP30093_P050 |
| Product Page |
www.avivasysbio.com/gfi1b-antibody-n-terminal-region-arp30093-p050.html |
| Name |
GFI1B Antibody - N-terminal region (ARP30093_P050) |
| Protein Size (# AA) |
330 amino acids |
| Molecular Weight |
38kDa |
| NCBI Gene Id |
8328 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Growth factor independent 1B transcription repressor |
| Alias Symbols |
BDPLT17, ZNF163B |
| Peptide Sequence |
Synthetic peptide located within the following region: MPRSFLVKSKMAHTYHQPRVQEDEPLWPPALTPVPRDQAPSNSPVLSTLF |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Huang,D.Y., et al., (2004) Nucleic Acids Res. 32 (13), 3935-3946 |
| Description of Target |
GFI1B acts in the late stage of erythroid differentiation as a transcriptional repressor. GATA-1 and NF-Y both contribute to erythroid-specific transcriptional activation of the Gfi-1B promoter. This zinc finger protein mediates erythroid expansion and has a role in normal erythropoiesis. |
| Protein Interactions |
ZNRD1; EFEMP2; NSMF; IFFO1; RCHY1; TENC1; HECW1; MID2; CCDC85B; COPS5; RUNDC3A; PDLIM5; FBLN5; MATR3; PDE4DIP; BRE; PICK1; HGS; DNAJA3; KALRN; BECN1; LTBP4; VSNL1; TRIP6; TRAF1; TMF1; TAF1; ATXN2; TRIM27; PSMA3; NOTCH1; NELL2; NELL1; LAMB1; JAG2; HSPG2; H |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-GFI1B (ARP30093_P050) antibody |
| Blocking Peptide |
For anti-GFI1B (ARP30093_P050) antibody is Catalog # AAP30093 (Previous Catalog # AAPH00269) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human GFI1B |
| Uniprot ID |
Q5VTD9 |
| Protein Name |
Zinc finger protein Gfi-1b |
| Protein Accession # |
NP_004179 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_004188 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
GFI1B |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Goat, Horse, Pig |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 83%; Dog: 100%; Goat: 83%; Horse: 100%; Human: 100%; Mouse: 83%; Pig: 93%; Rat: 82% |
| Image 1 | Human Jurkat
 | WB Suggested Anti-GFI1B Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysate |
|
| Image 2 | Human kidney
 | Rabbit Anti-GFI1B Antibody
Catalog Number: ARP30093
Paraffin Embedded Tissue: Human Kidney
Cellular Data: Epithelial cells of renal tubule and renal corpuscle
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
| Image 3 | Human Heart
 | Rabbit Anti-GFI1B Antibody
Catalog Number: ARP30093
Paraffin Embedded Tissue: Human Heart
Cellular Data: Myocardial cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
| Image 4 | Mouse testis, Rat liver
 | Host: Rabbit
Target: GFI1B
Positive control (+): Mouse testis (M-TE)
Negative control (-): Rat liver (R-LI)
Antibody concentration: 1ug/ml |
|
