| Sku |
AAPS23201 |
| Price |
$99.00 |
| Name |
TNFRSF18 Peptide (AAPS23201) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
TNFRSF18 |
| Alias symbols |
AITR, GITR, GITR-D, CD357 |
| Gene id |
8784 |
| Description of target |
The protein encoded by TNFRSF18 is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death.The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| Swissprot id |
B1AME3 |
| Protein accession num |
NP_683700 |
| Nucleotide accession num |
NM_148902 |
| Protein size |
234 amino acids |
| Molecular weight |
23kDa |
| Application |
WB |
| Partner proteins |
TNFSF18,TRAF1,TRAF2,TRAF3,TNFRSF18,TRAF1,TRAF2,TRAF3 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Liu,B., (2008) J. Biol. Chem. 283 (13), 8202-8210 |
| Description |
This is a synthetic peptide designed for use in combination with anti-TNFRSF18 antibody (Catalog #: AVARP02052_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
