| Sku |
AAPP04355 |
| Price |
$99.00 |
| Name |
SMARCE1 Peptide - N-terminal region (AAPP04355) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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|
| Size |
100 ug |
| Gene |
SMARCE1 |
| Alias symbols |
BAF57 |
| Gene id |
6605 |
| Description of target |
SMARCE1 is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-72 BQ707908.1 667-738 73-2415 AK095047.1 40-2382 2416-2425 BC063700.1 2379-2388 |
| Swissprot id |
Q969G3 |
| Protein accession num |
NP_003070 |
| Nucleotide accession num |
NM_003079 |
| Protein size |
411 amino acids |
| Molecular weight |
47kDa |
| Application |
WB |
| Partner proteins |
DISC1,tax,ARID2,BAZ1B,BRMS1,ESR1,ESR2,NCOA1,NCOA2,NCOA3,NR3C1,RCOR1,RELB,SMAD1,SMARCA4,SRC,ACTB,ACTL6A,ARID1A,BAZ1B,ESR1,ESR2,Esr1,GATA1,KLF1,MECP2,NCOA1,NR3C1,RELB,SMARCA2,SMARCA4,SMARCB1,SMARCC1,SMARCC2,STAT2,TFE3 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Pan,H., (2007) Biochim. Biophys. Acta 1772 (9), 1075-1084 |
| Description |
This is a synthetic peptide designed for use in combination with anti-SMARCE1 antibody (Catalog #: ARP33313_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
