ZNF384 Peptide - C-terminal region (AAP88417)

Data Sheet
 
Sku AAP88417
Price 99
Name ZNF384 Peptide - C-terminal region (AAP88417)
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Size 100ug
Gene ZNF384
Alias symbols NP, CIZ, NMP4, CAGH1, ERDA2, TNRC1, CAGH1A
Gene id 171017
Description of target This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7.
Swissprot id Q8TF68
Protein accession num NP_001035009.1
Nucleotide accession num NM_001039920.2
Protein size 577 amino acids
Molecular weight 63 kDa
Species reactivity Human
Peptide sequence Synthetic peptide located within the following region: QASQASQQQQQQQQQQQQQQQQPPPHFQSPGAAPQGGGGGDSNPNPPPQC
Quality control The peptide is characterized by mass spectroscopy
Description This is a synthetic peptide designed for use in combination with anti- ZNF384 Antibody (ARP88417_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery International: 3-5 business days
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