| Sku |
AAP88009 |
| Price |
99 |
| Name |
MDM2 Peptide - middle region (AAP88009) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100ug |
| Gene |
MDM2 |
| Alias symbols |
HDMX, hdm2, ACTFS |
| Gene id |
4193 |
| Description of target |
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. |
| Swissprot id |
Q00987-8 |
| Protein accession num |
NP_001138811.1 |
| Nucleotide accession num |
NM_001145339.2 |
| Protein size |
430 amino acids |
| Molecular weight |
47 kDa |
| Species reactivity |
Human |
| Peptide sequence |
Synthetic peptide located within the following region: KSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGD |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Description |
This is a synthetic peptide designed for use in combination with anti- MDM2 Antibody (ARP88009_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
