Sku |
AAP87383 |
Price |
99 |
Name |
HDAC3 Peptide - C-terminal region (AAP87383) |
Purchase info |
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|
Size |
100ug |
Gene |
HDAC3 |
Alias symbols |
HD3, RPD3, RPD3-2 |
Gene id |
8841 |
Description of target |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. |
Swissprot id |
O15379 |
Protein accession num |
NP_003874.2 |
Nucleotide accession num |
NM_003883.3 |
Protein size |
428 amino acids |
Molecular weight |
49 kDa |
Species reactivity |
Human |
Peptide sequence |
Synthetic peptide located within the following region: IHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESDV |
Quality control |
The peptide is characterized by mass spectroscopy |
Description |
This is a synthetic peptide designed for use in combination with anti- HDAC3 Antibody (ARP87383_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |