CDH5 Peptide - C-terminal region (AAP81377)

Data Sheet
 
Sku AAP81377
Price 99
Name CDH5 Peptide - C-terminal region (AAP81377)
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Size 100ug
Gene CDH5
Alias symbols 7B4, CD144
Gene id 1003
Description of target This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.
Swissprot id P33151-2
Protein accession num NP_001786.2
Nucleotide accession num NM_001795.3
Protein size 669 amino acids
Molecular weight 73 kDa
Species reactivity Human
Peptide sequence Synthetic peptide located within the following region: MIEVKKDEADHDGDGPPYDTLHIYGYEGSESIAESLSSLGTDSSDSDVDY
Quality control The peptide is characterized by mass spectroscopy
Description This is a synthetic peptide designed for use in combination with anti- CDH5 Antibody (ARP81377_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery International: 3-5 business days
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