TNFSF15 Peptide - C-terminal region (AAP80865)

Data Sheet
 
Sku AAP80865
Price 99
Name TNFSF15 Peptide - C-terminal region (AAP80865)
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Size 100ug
Gene TNFSF15
Alias symbols TL1, TL1A, VEGI, TNLG1B, VEGI192A
Gene id 9966
Description of target The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene.
Swissprot id O95150-2
Protein accession num NP_001191273.1
Nucleotide accession num NM_001204344.1
Protein size 192 amino acids
Molecular weight 21 kDa
Species reactivity Human
Peptide sequence Synthetic peptide located within the following region: CEVGSNWFQPIYLGAMFSLQEGDKLMVNVSDISLVDYTKEDKTFFGAFLL
Quality control The peptide is characterized by mass spectroscopy
Description This is a synthetic peptide designed for use in combination with anti- TNFSF15 Antibody (ARP80865_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery International: 3-5 business days
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