H2AFZ Peptide - N-terminal region (AAP74551)

Data Sheet
 
Sku AAP74551
Price 99
Name H2AFZ Peptide - N-terminal region (AAP74551)
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Size 100ug
Gene H2AFZ
Alias symbols H2AZ, H2A.z, H2A/z, H2A.Z-1
Gene id 3015
Description of target Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.
Swissprot id P0C0S5
Protein accession num NP_002097
Protein size 128 amino acids
Molecular weight 14kDa
Species reactivity Human
Peptide sequence Synthetic peptide located within the following region: GKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAV
Partner proteins UBC; ASB9; ASB16; WWOX; ZBTB1; OGFOD1; TRNT1; ACAA2; NOL3; EZR; PYGL; PSMD9; FH; UBD; PAN2; HIST1H3B; CENPA; MAGEC1; SUMO1; SUMO3; NEDD8; EPC1; MEAF6; ACTR6; EP400; DMAP1; MRGBP; ING3; MORF4L1; RUVBL2; SRCAP; KAT5; RUVBL1; TRRAP; YEATS4; VPS72; ACTL6A; HI
Quality control The peptide is characterized by mass spectroscopy
Key reference N/A
Description This is a synthetic peptide designed for use in combination with anti-H2AZ Antibody (ARP74551_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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