Sku |
AAP74551 |
Price |
99 |
Name |
H2AFZ Peptide - N-terminal region (AAP74551) |
Purchase info |
To purchase this peptide:
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|
Size |
100ug |
Gene |
H2AFZ |
Alias symbols |
H2AZ, H2A.z, H2A/z, H2A.Z-1 |
Gene id |
3015 |
Description of target |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. |
Swissprot id |
P0C0S5 |
Protein accession num |
NP_002097 |
Protein size |
128 amino acids |
Molecular weight |
14kDa |
Species reactivity |
Human |
Peptide sequence |
Synthetic peptide located within the following region: GKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAV |
Partner proteins |
UBC; ASB9; ASB16; WWOX; ZBTB1; OGFOD1; TRNT1; ACAA2; NOL3; EZR; PYGL; PSMD9; FH; UBD; PAN2; HIST1H3B; CENPA; MAGEC1; SUMO1; SUMO3; NEDD8; EPC1; MEAF6; ACTR6; EP400; DMAP1; MRGBP; ING3; MORF4L1; RUVBL2; SRCAP; KAT5; RUVBL1; TRRAP; YEATS4; VPS72; ACTL6A; HI |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
N/A |
Description |
This is a synthetic peptide designed for use in combination with anti-H2AZ Antibody (ARP74551_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |