| Sku |
AAP74198 |
| Price |
$99.00 |
| Name |
SAFB Peptide - middle region (AAP74198) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100ug |
| Gene |
SAFB |
| Alias symbols |
HAP, HET, SAF-B, SAFB1, SAB-B1, SAF-B1 |
| Gene id |
6294 |
| Description of target |
This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Swissprot id |
Q15424-2 |
| Protein size |
848 amino acids |
| Molecular weight |
93kDa |
| Species reactivity |
Human |
| Application |
WB |
| Peptide sequence |
Synthetic peptide located within the following region: TELHGKMISVEKAKNEPVGKKTSDKRDSDGKKEKSSNSDRSTNLKRDDKC |
| Partner proteins |
SUMO3; STAU1; UBC; LGR4; SUMO1; EED; rev; TP63; IL7R; CSNK2A1; MAP1LC3A; TP53BP1; TRMT112; TMOD2; RBMX; NCSTN; ACIN1; SMU1; U2AF2; CPSF6; GCN1L1; UTP14A; USP39; SAP18; VTN; U2AF1; TPBG; SURF4; SON; SRSF7; PRKAR1A; ABCC1; LAMP2; SEPT7; AK2; ACAT1; ZC3H18; |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
N/A |
| Description |
This is a synthetic peptide designed for use in combination with anti-SAFB1 Antibody (ARP74198_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
