VCL Peptide - C-terminal region (AAP61098)

Data Sheet
 
Sku AAP61098
Price $99
Name VCL Peptide - C-terminal region (AAP61098)
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Size 100ug
Gene VCL
Alias symbols MV, MVCL, CMD1W, CMH15, HEL114
Gene id 7414
Description of target Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
Swissprot id P18206
Protein accession num NP_054706
Protein size 1134 amino acids
Molecular weight 124kDa
Species reactivity Human
Application WB
Peptide sequence Synthetic peptide located within the following region: QPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTI
Partner proteins VCL; UBC; TEKT1; SUMO2; ASB7; CTPS1; GINS3; UBFD1; ISOC1; DCPS; ERP44; PDCD10; FERMT2; YWHAQ; TUBB3; PDIA4; STK24; YWHAZ; YWHAH; YWHAG; YWHAE; XPO1; SNRPF; RAP1GDS1; PPP5C; PPP1R2; PFAS; PDHA1; MSN; HSPA9; HSPA5; GSS; SFN; GNAI3; G6PD; EIF5; ECHS1; TBCB;
Quality control The peptide is characterized by mass spectroscopy
Key reference N/A
Description This is a synthetic peptide designed for use in combination with anti-VINC Antibody (ARP61098_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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