Sku |
AAP61098 |
Price |
$99 |
Name |
VCL Peptide - C-terminal region (AAP61098) |
Purchase info |
To purchase this peptide:
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|
Size |
100ug |
Gene |
VCL |
Alias symbols |
MV, MVCL, CMD1W, CMH15, HEL114 |
Gene id |
7414 |
Description of target |
Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. |
Swissprot id |
P18206 |
Protein accession num |
NP_054706 |
Protein size |
1134 amino acids |
Molecular weight |
124kDa |
Species reactivity |
Human |
Application |
WB |
Peptide sequence |
Synthetic peptide located within the following region: QPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTI |
Partner proteins |
VCL; UBC; TEKT1; SUMO2; ASB7; CTPS1; GINS3; UBFD1; ISOC1; DCPS; ERP44; PDCD10; FERMT2; YWHAQ; TUBB3; PDIA4; STK24; YWHAZ; YWHAH; YWHAG; YWHAE; XPO1; SNRPF; RAP1GDS1; PPP5C; PPP1R2; PFAS; PDHA1; MSN; HSPA9; HSPA5; GSS; SFN; GNAI3; G6PD; EIF5; ECHS1; TBCB; |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
N/A |
Description |
This is a synthetic peptide designed for use in combination with anti-VINC Antibody (ARP61098_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |