CSTB Peptide - N-terminal region (AAP59177)

Data Sheet
 
Sku AAP59177
Old sku AAPP45145
Price $99.00
Name CSTB Peptide - N-terminal region (AAP59177)
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Size 100ug
Gene CSTB
Alias symbols CST6, EPM1, PME, STFB, ULD, EPM1A
Gene id 1476
Description of target CSTB is a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in CSTB gene are responsible for the primary defects in patients with progressive myoclonic epilepsy a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy.
Swissprot id P04080
Protein accession num NP_000091
Nucleotide accession num NM_000100
Protein size 98 amino acids
Molecular weight 11kDa
Species reactivity Human
Application WB
Peptide sequence ADQVRSQLEEKENKKFPVFKAVSFKSQVVAGTNYFIKVHVGDEDFVHLRV
Partner proteins CTSB,CTSD,CTSH,CTSL1,CST3,CTSB,CTSH,VHL
Quality control The peptide is characterized by mass spectroscopy
Key reference N/A
Description This is a synthetic peptide designed for use in combination with anti-CSTB Antibody(ARP59177_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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