CALR Peptide - middle region (AAP58880)

Data Sheet
 
Sku AAP58880
Old sku AAPP44827
Price $99.00
Name CALR Peptide - middle region (AAP58880)
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Size 100ug
Gene CALR
Alias symbols CRT, FLJ26680, RO, SSA, cC1qR
Gene id 811
Description of target Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium.
Swissprot id P27797
Protein accession num NP_004334
Nucleotide accession num NM_004343
Protein size 417 amino acids
Molecular weight 46kDa
Species reactivity Human
Application WB
Peptide sequence ASKPEDWDERAKIDDPTDSKPEDWDKPEHIPDPDAKKPEDWDEEMDGEWE
Partner proteins CALR,HLA-A,PDIA3,TSHR,APOB,APP,AR,B2M,CALR,CD1D,F5,F8,FBN1,FGB,HLA-C,ITGA2B,ITGA3,ITGAV,LPL,LRP1,MBL2,MTNR1A,NKX2-1,NR3C1,PDIA2,PDIA3,PLAT,PLP1,PRF1,SCARF1,SLC2A1,SLC6A4,SUMO4,TAPBP,TF,THBS1,TSHR,VWF,APOB,APP,AR,CANX,CD1D,CD40,ELF3,EPB41,F5,FGB,H2AFX,LRP1
Quality control The peptide is characterized by mass spectroscopy
Key reference N/A
Description This is a synthetic peptide designed for use in combination with anti-CALR Antibody(ARP58880_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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