Sku |
AAP58763 |
Old sku |
AAPP38530 |
Price |
$99.00 |
Name |
SHB Peptide - N-terminal region (AAP58763) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
SHB |
Alias symbols |
RP11-3J10.8, bA3J10.2 |
Gene id |
6461 |
Description of target |
SHB is the adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. SHB may play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. SHB may also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. SHB may also regulate IRS1 and IRS2 signaling in insulin-producing cells. |
Swissprot id |
Q15464 |
Protein accession num |
NP_003019 |
Nucleotide accession num |
NM_003028 |
Protein size |
509 amino acids |
Molecular weight |
55kDa |
Application |
WB |
Partner proteins |
EPS8,FGFR1,PDGFRB,PIK3R1,SRC,src,CRK,EPS8,GRAP2,GRB2,IL2RB,IL2RG,JAK1,JAK3,KDR,LAT,LCP2,PDGFRA,PIK3R1,PLCG1,SLC39A1,SRC,VAV1,ZAP70,CRK,EPS8,FGFR1,GRB2,IL2RB,IL2RG,JAK1,JAK3,KDR,LAT,LCP2,PIK3R1,PLCG1,SRC,VAV1,ZAP70 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Kriz,V., (2006) J. Biol. Chem. 281 (45), 34484-34491 |
Description |
This is a synthetic peptide designed for use in combination with anti-SHB antibody (Catalog #: ARP58763_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |