SHB Peptide - N-terminal region (AAP58763)

Data Sheet
 
Sku AAP58763
Old sku AAPP38530
Price $99.00
Name SHB Peptide - N-terminal region (AAP58763)
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Size 100 ug
Gene SHB
Alias symbols RP11-3J10.8, bA3J10.2
Gene id 6461
Description of target SHB is the adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. SHB may play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. SHB may also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. SHB may also regulate IRS1 and IRS2 signaling in insulin-producing cells.
Swissprot id Q15464
Protein accession num NP_003019
Nucleotide accession num NM_003028
Protein size 509 amino acids
Molecular weight 55kDa
Application WB
Partner proteins EPS8,FGFR1,PDGFRB,PIK3R1,SRC,src,CRK,EPS8,GRAP2,GRB2,IL2RB,IL2RG,JAK1,JAK3,KDR,LAT,LCP2,PDGFRA,PIK3R1,PLCG1,SLC39A1,SRC,VAV1,ZAP70,CRK,EPS8,FGFR1,GRB2,IL2RB,IL2RG,JAK1,JAK3,KDR,LAT,LCP2,PIK3R1,PLCG1,SRC,VAV1,ZAP70
Quality control The peptide is characterized by mass spectroscopy
Key reference Kriz,V., (2006) J. Biol. Chem. 281 (45), 34484-34491
Description This is a synthetic peptide designed for use in combination with anti-SHB antibody (Catalog #: ARP58763_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
Protocol
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