Sku |
AAP58728 |
Old sku |
AAPP36424 |
Price |
$99.00 |
Name |
TMED10 Peptide - middle region (AAP58728) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
TMED10 |
Alias symbols |
P24(DELTA), S31I125, S31III125, TMP21, Tmp-21-I, p23 |
Gene id |
10972 |
Description of target |
TMED10 is involved in vesicular protein trafficking.This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. |
Swissprot id |
P49755 |
Protein accession num |
NP_006818 |
Nucleotide accession num |
NM_006827 |
Protein size |
219 amino acids |
Molecular weight |
24kDa |
Application |
WB |
Partner proteins |
APH1A,ARF1,NCSTN,PSENEN,TMED2,GORASP2 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Dolcini,V., (2008) Biochem. Biophys. Res. Commun. 371 (1), 69-74 |
Description |
This is a synthetic peptide designed for use in combination with anti-TMED10 antibody (Catalog #: ARP58728_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |