TMED10 Peptide - middle region (AAP58728)

Data Sheet
 
Sku AAP58728
Old sku AAPP36424
Price $99.00
Name TMED10 Peptide - middle region (AAP58728)
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Size 100 ug
Gene TMED10
Alias symbols P24(DELTA), S31I125, S31III125, TMP21, Tmp-21-I, p23
Gene id 10972
Description of target TMED10 is involved in vesicular protein trafficking.This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Swissprot id P49755
Protein accession num NP_006818
Nucleotide accession num NM_006827
Protein size 219 amino acids
Molecular weight 24kDa
Application WB
Partner proteins APH1A,ARF1,NCSTN,PSENEN,TMED2,GORASP2
Quality control The peptide is characterized by mass spectroscopy
Key reference Dolcini,V., (2008) Biochem. Biophys. Res. Commun. 371 (1), 69-74
Description This is a synthetic peptide designed for use in combination with anti-TMED10 antibody (Catalog #: ARP58728_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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